Kids' constipation drug tested for long-term safety

NCT ID NCT04166058

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This study tested the long-term safety of an oral medication called linaclotide in children and teenagers (ages 6-17) with functional constipation or irritable bowel syndrome with constipation (IBS-C). The 381 participants took the medication for either 24 or 52 weeks to see what side effects might occur with extended use. The main goal was to monitor for any health problems that developed while taking the drug.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AIM Trials /ID# 236364

Plano, Texas, 75093, United States
Accellacare of Knoxville /ID# 234462

Jefferson City, Tennessee, 37760, United States
Advanced Research Center /ID# 237960

Anaheim, California, 92805, United States
Advanced Research for Health Improvement /ID# 238253

Naples, Florida, 34102-5430, United States
Advantage Clinical Trials /ID# 237932

The Bronx, New York, 10468, United States
Amedica Research Institute Inc /ID# 234666

Hialeah, Florida, 33013, United States
Applied Research Center of Arkansas /ID# 238069

Little Rock, Arkansas, 72212-4187, United States
Bluewater Clinical Research Group Inc /ID# 234618

Sarnia, Ontario, N7T 4X3, Canada
Central Research Associates /ID# 237953

Birmingham, Alabama, 35205, United States
Children's Ctr Digestive, US /ID# 237574

Atlanta, Georgia, 30342, United States
Children's Healthcare of Atlanta - Ferry Rd /ID# 237005

Atlanta, Georgia, 30342-1605, United States
Childrens National Medical Center /ID# 234417

Washington D.C., District of Columbia, 20010-2916, United States
ClinPoint Trials /ID# 236615

Waxahachie, Texas, 75165-1430, United States
Clinical Research Institute /ID# 234702

Stockbridge, Georgia, 30281, United States
Clinical Research Partners, LLC /ID# 237158

Richmond, Virginia, 23220-4459, United States
Coastal Pediatric Research - Summerville /ID# 234674

Summerville, South Carolina, 29486, United States
Coastal Pediatric Research - West Ashley B /ID# 234678

Charleston, South Carolina, 29414, United States
Columbia University Irving Medical Center /ID# 235686

New York, New York, 10032, United States
Cook Children's Med. Center /ID# 237536

Fort Worth, Texas, 76104, United States
Cullen Research /ID# 234482

Houston, Texas, 77051, United States
David M. Headley, MD, P.A. /ID# 238216

Port Gibson, Mississippi, 39150-2024, United States
Dolphin Medical Research /ID# 234676

Doral, Florida, 33172, United States
Duplicate_Academisch Medisch Centrum /ID# 237116

Amsterdam, North Holland, 1105 AZ, Netherlands
Duplicate_Center for Clinical Trials LLC /ID# 234629

Paramount, California, 90723, United States
Duplicate_Chrysalis Clinical Research /ID# 234515

St. George, Utah, 84790, United States
Duplicate_Frontier Clinical Research /ID# 237923

Smithfield, Pennsylvania, 15478, United States
Duplicate_Multicare Institute for Research and Innovation /ID# 236979

Tacoma, Washington, 98405, United States
East Carolina University - Brody School of Medicine /ID# 237509

Greenville, North Carolina, 27834, United States
Elite Clinical Research /ID# 234651

Miami, Florida, 33144, United States
Frontier Clinical Research, LLC - Scottdale /ID# 238022

Scottdale, Pennsylvania, 15683, United States
G & L Research, LLC /ID# 238093

Foley, Alabama, 36535, United States
GI associates and Endoscopy Ce /ID# 237969

Flowood, Mississippi, 39232, United States
Hadassah Hebrew University Hospital - Ein Kerem /ID# 234735

Jerusalem, Jerusalem, 91120, Israel
Health Research of Hampton Roads, Inc. (HRHR) /ID# 237252

Newport News, Virginia, 23606, United States
HealthStar Research of Hot Springs PLLC /ID# 234608

Hot Springs, Arkansas, 71913, United States
IPS Research Company /ID# 237669

Oklahoma City, Oklahoma, 73106, United States
KU Wichita Center for Clinical Research /ID# 234500

Wichita, Kansas, 67214, United States
Kindred Medical Institute, LLC /ID# 237367

Corona, California, 92879, United States
London Health Sciences Center- University Hospital /ID# 234309

London, Ontario, N6A 5W9, Canada
Lynn Institute of Denver /ID# 238086

Aurora, Colorado, 80012, United States
MNGI Digestive Health, P. A. /ID# 234437

Minneapolis, Minnesota, 55413-2195, United States
Medclinical Research Partners LLC/ Foundation Pediatrics /ID# 234566

East Orange, New Jersey, 07018, United States
Medical Ctr for Clin Research /ID# 236911

San Diego, California, 92108, United States
Michael W. Simon, MD, PSC /ID# 236516

Lexington, Kentucky, 40517, United States
My Preferred Research LLC /ID# 237943

Miami, Florida, 33155, United States
Nemours Children's Hospital /ID# 234429

Orlando, Florida, 32827-7884, United States
Nemours Childrens Specialty Care /ID# 237991

Jacksonville, Florida, 32207, United States
Office of Maria Ona /ID# 234539

Franklin, Virginia, 23851, United States
Oviedo Medical Research /ID# 234692

Oviedo, Florida, 32765, United States
PMG Research of Piedmont Healthcare-Statesville /ID# 238257

Statesville, North Carolina, 28625, United States
Pediatric & Adult Research Center /ID# 234681

Orlando, Florida, 32825, United States
Pioneer Research Solutions - Houston /ID# 236935

Houston, Texas, 77099-4307, United States
Preferred Research Partners /ID# 237109

Little Rock, Arkansas, 72211, United States
Private Practice - Dr. Craig Spiegel /ID# 234545

Bridgeton, Missouri, 63044, United States
Prohealth Research Center /ID# 234659

Doral, Florida, 33166, United States
Rhode Island Hospital /ID# 237861

Providence, Rhode Island, 02903, United States
River Birch Research Alliance /ID# 237963

Blue Ridge, Georgia, 30513, United States
Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 236342

Stockbridge, Georgia, 30281, United States
South Miami Medical & Research Group Inc. /ID# 234654

Miami, Florida, 33155, United States
Stouffville Medical Centre /ID# 234619

Stouffville, Ontario, L4A 1H2, Canada
Sun Research Institute /ID# 236932

San Antonio, Texas, 78215, United States
The Baruch Padeh Medical Center Poriya /ID# 234768

Tiberias, Northern District, 15208, Israel
The Center for Clinical Trials Inc. /ID# 234605

Saraland, Alabama, 36571, United States
The Chaim Sheba Medical Center /ID# 236760

Ramat Gan, Tel Aviv, 5265601, Israel
The Jackson Clinic, PA /ID# 236772

Jackson, Tennessee, 38305, United States
Treken Primary Care /ID# 234645

Atlanta, Georgia, 30315, United States
Univ Oklahoma HSC /ID# 237546

Oklahoma City, Oklahoma, 73104, United States
University of New Mexico /ID# 236983

Albuquerque, New Mexico, 87102-4517, United States
Valencia Medical & Research Center /ID# 234671

Miami, Florida, 33165, United States
Valley Institute of Research /ID# 234475

Harlingen, Texas, 78550, United States
Vilo Research Group Inc /ID# 238228

Houston, Texas, 77017-2337, United States
Virgo Carter Pediatrics /ID# 234518

Silver Spring, Maryland, 20910, United States

Conditions

Explore the condition pages connected to this study.

FUNCTIONAL CONSTIPATION IRRITABLE BOWEL SYNDROME WITH CONSTIPATION