Hope for kids with rare liver disease: 2-Year drug trial aims to prevent transplants

NCT ID NCT05426733

Summary

This study is a 2-year follow-up to see if a drug called odevixibat can help children with biliary atresia live longer without needing a liver transplant. It will track about 180 children who were in a previous study to measure the drug's long-term safety and its effect on liver health and growth. The main goal is to see if the treatment can control the disease and delay or prevent the need for major surgery.

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Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    Bergamo, Italy

  • Akdeniz University Medical Faculty

    Antalya, Turkey (Türkiye)

  • Azienda Ospedaliera di Padova

    Padua, Italy

  • Bicêtre Hospital

    Le Kremlin-Bicêtre, France

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • CHU Sainte-Justine

    Montreal, Canada

  • Charité - Universitätsmedizin Berlin

    Berlin, Germany

  • Children's Healhcare of Atlanta- Emory University school of medicine

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Fudan University

    Shanghai, China

  • Children's Mercy Hospital and Clinics

    Kansas City, Missouri, 64108, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Columbia University Medical Center New York Presbyterian Morgan Stanley-Komansky Childrens Hospital

    New York, New York, 10032, United States

  • Guangzhou Women And Childrens Medical Center

    Guangdong, China

  • Hacettepe İhsan Doğramacı Children's Hospital

    Ankara, Turkey (Türkiye)

  • Hassenfeld Children's Hospital at NYU Langone

    New York, New York, 10016, United States

  • Hospital Raja Perempuan Zainab II

    Kota Bharu, Malaysia

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Indiana University school of Medicine

    Indianapolis, Indiana, 46202, United States

  • Instytut Pomnik-Centrum Zdrowia Dziecka

    Warsaw, Poland

  • Istanbul University Istanbul Medical Faculty Hospital

    Istanbul, Turkey (Türkiye)

  • Royal Children's Hospital

    Parkville, 3052, Australia

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Seoul National University Childrens Hospital

    Seoul, South Korea

  • Starship Child Health, Te Whatu Ora - Health New Zealand

    Auckland, 1023, New Zealand

  • The Childrens Hospital at Montefiore Albert Einstein School of Medicine

    The Bronx, New York, 10467, United States

  • The Hospital for Sick Children

    Toronto, Canada

  • University Children´s Hospital Tuebingen

    Tübingen, Germany

  • University Malaya Medical Centre

    Kuala Lumpur, 59100, Malaysia

  • University Medical Center Groningen

    Groningen, Netherlands

Conditions

Explore the condition pages connected to this study.