Extended trial tests promising drug to control rare liver disease
NCT ID NCT05899673
Summary
This study aims to learn about the long-term safety of a drug called fazirsiran for people with liver disease caused by Alpha-1 antitrypsin deficiency. It allows 31 participants from previous fazirsiran studies to continue receiving the drug every three months. The main goal is to monitor for side effects over time, while also checking if the treatment helps reduce or slow down liver scarring.
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Contacts and locations
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Locations
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Addenbrooke's Hospital
Cambridge, CB2 0QQ, United Kingdom
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Hospital Nélio Mendonça
Funchal, 9000-168, Portugal
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Medical University of South Carolina - Hollings Cancer Center - PPDS
Charleston, South Carolina, 29425-8900, United States
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Medizinische Universitat Wien (Medical University of Vienna)
Vienna, A-1090, Austria
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Royal Infirmary of Edinburgh - PPDS
Edinburgh, EH16 4SA, United Kingdom
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Stanford Medicine Outpatient Center
Redwood City, California, 94063, United States
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UCSD Altman Clinical and Translational Research Institute
La Jolla, California, 92037-1337, United States
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UF Clinical and Translational Science Institute
Gainesville, Florida, 32610-3010, United States
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University Of Iowa Hospitals And Clinics
Iowa City, Iowa, 52242-1009, United States
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Universitätsklinikum der RWTH Aachen
Aachen, North Rhine-Westphalia, 52074, Germany
Conditions
Explore the condition pages connected to this study.