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HIV study tracks kids treated early for clues to remission

NCT ID NCT05154513

Completed Knowledge-focused Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 163 children with HIV who started treatment within 12 weeks of birth. Researchers measured their growth, immune health, and virus levels over about seven years. No new treatment was given; the goal was to gather long-term data to help design future studies aiming for HIV remission or cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could provide crucial data to guide future research aimed at HIV remission or cure in children.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly test any new therapy. The results may not apply to all children with HIV.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTION

Contacts and locations

Locations

  • 30300, Umlazi Clinical Research Site

    Durban, South Africa

  • 31798, Baylor-Uganda Clinical Research Site

    Kampala, Uganda

  • 5030, Emory University School of Medicine Clinical Research Site

    Atlanta, Georgia, 30322, United States

  • 5055, South Florida CDTC Fort Lauderdale Clinical Research Site

    Fort Lauderdale, Florida, 33316, United States

  • 5071, Instituto de Puericultura e Pediatria Martagao Gesteira Clinical Research Site

    Rio de Janeiro, Brazil

  • 5121, Kenya Medical Research Institute/Walter Reed Project Clinical Research Center Kericho Clinical Research Site

    Kericho, Kenya

  • 5128, Texas Children's Hospital Clinical Research Site

    Houston, Texas, 77030, United States

  • 8051, Wits RHI Shandukani Research Centre Clinical Research Site

    Johannesburg, South Africa

  • Chiang Rai Regional Hospital (5116)

    Chiang Rai, Thailand

  • College of Med. JHU CRS (30301)

    Blantyre, Malawi

  • David Geffen School of Medicine at UCLA (CRS 5112)

    Los Angeles, California, 90095, United States

  • Family Clinical Research Unit (FAM-CRU) CRS (8950)

    Tygerberg Hills, South Africa

  • Gaborone CRS 12701

    Gaborone, Botswana

  • Harare Family Care (31890)

    Harare, Zimbabwe

  • Hospital Geral De Nova Igaucu (5097)

    Rio de Janeiro, Brazil

  • Hospital dos Servidores Rio de Janeiro

    Rio de Janeiro, Brazil

  • Kilimanjaro Christian Medical Centre (5118)

    Moshi, Tanzania

  • Les Centres GHESKIO (30022)

    Port-au-Prince, Haiti

  • Molepolole Prevention/Treatment Trials CRS 12702

    Molepolole, Botswana

  • Ribeirao Preto Medical School, University of Sao Paulo (5074)

    São Paulo, Brazil

  • School of Medicine, University of Minas Gerais - FUNDEP (5073)

    Belo Horizonte, Brazil

  • Seke North CRS 30306

    Chitungwiza, Zimbabwe

  • Siriraj Hospital Mahidol University CRS (5115)

    Bangkok, Ratchathewi, 10700, Thailand

  • Soweto IMPAACT CRS (8052)

    Johannesburg, Gauteng, South Africa

  • St. Mary's CRS 30303

    Chitungwiza, Zimbabwe

  • Univ of Miami Pediatric/Perinatal HIV/AIDS (5127)

    Miami, Florida, 33136, United States

  • University of Colorado (5052)

    Aurora, Colorado, 80045, United States

  • University of North Carolina Lilongwe (12001)

    Lilongwe, Malawi

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