New hope for calming Alzheimer's agitation: Long-Term drug safety tested

NCT ID NCT06937229

Recruiting now Symptom relief Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study aims to understand the long-term safety and side effects of two drug combinations, KarXT and KarX-EC, for treating agitation in people with Alzheimer's disease. It is open to 600 participants who have already completed one of two previous related studies. The main goal is to monitor for any health problems that might occur while taking these medications over an extended period.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Phone: •••-•••-•••• Email: •••••@•••••
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Locations

Boston Center for Memory
RECRUITING

Newton, Massachusetts, 02459, United States

Contact Phone: •••-•••-••••
Epic Medical Research, LLC - Carrolton
RECRUITING

Carrollton, Texas, 75006, United States

Contact Phone: •••-•••-••••
Gangnam Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 06273, South Korea

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Imaging Endpoints
RECRUITING

Scottsdale, Arizona, 85258, United States

Contact Phone: •••-•••-••••
Kuramitsu Hospital
RECRUITING

Fukuoka, 819-0037, Japan

Contact Phone: •••-•••-••••
Local Institution - 0003
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Málaga, 29010, Spain
Local Institution - 0027
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Athens, 106 79, Greece
Local Institution - 1000
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Córdoba, 5006, Argentina

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Local Institution - 1001
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La Plata, Buenos Aires, 1900, Argentina

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Mar del Plata, Buenos Aires, B7602CBM, Argentina

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Buenos Aires, C1428AQK, Argentina

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Córdoba, 5000, Argentina

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Córdoba, 5004, Argentina

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Rosario, Santa Fe Province, S2000, Argentina

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Rio de Janeiro, 22270-060, Brazil

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Brasília, Federal District, 70200730, Brazil

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Curitiba, Paraná, 80230-130, Brazil

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Curitiba, Paraná, 80240-280, Brazil

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Porto Alegre, Rio Grande do Sul, 90560-032, Brazil

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São Paulo, 01228-000, Brazil

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Campinas, São Paulo, 13060-080, Brazil

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Porto Alegre, Rio Grande do Sul, 90430-001, Brazil

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Sofia, Sofia-Grad, 1113, Bulgaria

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Pleven, 5800, Bulgaria

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Varna, 9020, Bulgaria

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Razgrad, 7200, Bulgaria

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Toronto, Ontario, M4N 3M5, Canada

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Whitby, Ontario, L1N 5S9, Canada

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Hamilton, Ontario, ON L8M 1W9, Canada

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Toronto, Ontario, M6J 1H4, Canada

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London, Ontario, N6A 5A5, Canada

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Pátrai, Achaḯa, 26504, Greece

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Ioannina, 45500, Greece

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Athens, Attica, 11527, Greece

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Chaïdári, Attikí, 124 62, Greece

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Thessaloniki, 54645, Greece

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Athens, Attica, 115 26, Greece

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Athens, 106 79, Greece

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Athens, 15125, Greece

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Kolkata, West Bengal, 700054, India

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Hyderabad, Andhra Pradesh, 500 034, India

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Hyderabad, Telangana, 500082, India

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Varanasi, Uttar Pradesh, 221005, India

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Ahmedabad, Gujarat, 380060, India

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Delhi, 110 095, India

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Hadano, Kanagawa, 257-0003, Japan

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Sakai, Osaka, 590-0018, Japan

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Bunkyo-ku, Tokyo, 113-8603, Japan

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Kawasaki, Kanagawa, 213-8507, Japan

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Shimotsuke-shi, Tochigi, 329-0498, Japan

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Monterrey, Nuevo León, 66460, Mexico

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Tlalnepantla, 54055, Mexico

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Saltillo, Coahuila, 25000, Mexico

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Guadalajara, Jalisco, 44600, Mexico

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Mexico City, Mexico City, 14269, Mexico

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Mexico City, 10200, Mexico

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San Luis Potosí City, 78216, Mexico

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Mexico City, Mexico City, 14090, Mexico

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Monterrey, Nuevo León, 64623, Mexico

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Torres Vedras, 2560-280, Portugal

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Coimbra, 3049, Portugal

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Guimarães, 4835-044, Portugal

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Senhora da Hora, 4464-513, Portugal

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Lisbon, 1649-035, Portugal

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Bucharest, București, 041919, Romania

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Bucharest, 010825, Romania

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Bucharest, București, 041919, Romania

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Bucharest, București, 041919, Romania

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Iași, 700282, Romania

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Bucharest, București, 041919, Romania

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Bucharest, 060222, Romania

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Local Institution - 1460
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Sanpetru /Brasov, 507190, Romania

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Local Institution - 1461
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Constanța, 90123, Romania

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Sibiu, 550082, Romania

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Local Institution - 1500
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Salamanca, 37007, Spain

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Zaragoza, 50012, Spain

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Málaga, 29010, Spain

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Seville, 41009, Spain

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Terrassa, 8221, Spain

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Madrid, 28040, Spain

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Valladolid, 47012, Spain

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Pamplona, 31008, Spain

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Madrid, 28006, Spain

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Elche (alicante), 03203, Spain

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Getxo, Bizkaia, 48993, Spain

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Zagreb, 10000, Croatia

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Split, HR-21000, Croatia

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Varaždin, 42000, Croatia

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Zagreb, City of Zagreb, 10000, Croatia

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Rijeka, 51000, Croatia

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Miami, Florida, 33122, United States

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Miami, Florida, 33166, United States

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Local Institution - 1618
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Miami, Florida, 33135, United States

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Local Institution - 1620
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Troy, Michigan, 48085, United States

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Local Institution - 1635
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Orlando, Florida, 32807, United States

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Local Institution - 1636
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Gaithersburg, Maryland, 20877, United States

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Local Institution - 1637
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La Jolla, California, 92037, United States

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Local Institution - 1640
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Tulsa, Oklahoma, 74136, United States

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Local Institution - 1643
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El Paso, Texas, 79912, United States

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Local Institution - 1644
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Seattle, Washington, 98122, United States

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Local Institution - 1646
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Bennington, Vermont, 05201-9810, United States

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Local Institution - 1647
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West Long Branch, New Jersey, 07764, United States

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Las Vegas, Nevada, 89119, United States

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Walnut Creek, California, 94596, United States

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Columbia, South Carolina, 29205, United States

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Spokane, Washington, 99201, United States

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Local Institution - 1656
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New Windsor, New York, 12553, United States

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Local Institution - 1657
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Anaheim, California, 92805, United States

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Woodmere, New York, 11598-1739, United States

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Pomona, California, 91767, United States

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Local Institution - 1750
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Taipei, 112, Taiwan

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Tainan, Taiana, 704, Taiwan

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Taoyuan District, 333, Taiwan

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Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan

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Taipei, 100229, Taiwan

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Local Institution - 2000
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Córdoba, 5000, Argentina

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Mendoza, 5502, Argentina

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Córdoba, 5000, Argentina

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Córdoba, X5003DCE, Argentina

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Buenos Aires, 1199, Argentina

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Ciudad Autonoma de Buenos Aires, Buenos Aires, 1058, Argentina

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Buenos Aires, Buenos Aires F.D., 1133, Argentina

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Santiago, Santiago Metropolitan, 7500710, Chile

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Santiago, Santiago Metropolitan, 8330024, Chile

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Antofagasta, 1270244, Chile

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Vitacura, Santiago Metropolitan, 2511433, Chile

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Viña del Mar, Región de Valparaíso, 2511433, Chile

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Prague, Praha 6, 160 00, Czechia

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Choceň, 565 01, Czechia

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Prague, 100 000, Czechia
Local Institution - 2103
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Brno, South Moravian, 628 00, Czechia

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Pilsen, 301 00, Czechia

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Prague, 100 00, Czechia
Local Institution - 2106
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Prague, Praha 8, 18600, Czechia

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Olomouc, Olomoucký kraj, 779 00, Czechia

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Rychnov nad Kněžnou, 516 01, Czechia

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Toulouse, Haute-Garonne, 31000, France

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Villeurbanne, Rhône, 69100, France

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Paris, 75010, France

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Lille, 59037, France

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Strasbourg, 67091, France

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Limoges, 87042, France

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Montpellier, 34295, France

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Local Institution - 2201
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Düsseldorf, 40221, Germany

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Halle, 06120, Germany

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Westerstede, 26655, Germany

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Győr, Győr-Moson-Sopron, 0, Hungary

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Budapest, 1088, Hungary
Local Institution - 2252
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Debrecen, 4032, Hungary

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Budapest, 1088, Hungary

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Gyöngyös, Heves County, 3200, Hungary

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Budapest, 1036, Hungary

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Saint Paul, Minnesota, 55130, United States

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Kalocsa, Bács-Kiskun county, 6300, Hungary

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Local Institution - 2300
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Ramat Gan, 5265601, Israel

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Jerusalem, 91120, Israel

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Petch Tikva, IL, 49100, Israel

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Netanya, 4244916, Israel

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Rishon Le'Tzion, 7590653, Israel

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Ramat Gan, 5262000, Israel

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Pisa, PI, 56126, Italy

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Naples, Campania, 80131, Italy

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Rome, Lazio, 00189, Italy

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Milan, Lombardy, 20149, Italy

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Rome, Lazio, 00185, Italy

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Isernia, 86077, Italy
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Brescia, 25123, Italy

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Roma, 00168, Italy

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Deagu, Taegu-Kwangyǒkshi, 41404, South Korea

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Incheon, Incheon Gwang'yeogsi, 22332, South Korea

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Seoul, 05505, South Korea

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Seoul, Seoul-teukbyeolsi [Seoul], 05030, South Korea

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Seoul, 07061, South Korea

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Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea
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Incheon, 405-760, South Korea

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Poznan, Greater Poland Voivodeship, 61-485, Poland

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Lublin, 20-064, Poland

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Lublin, 20-064, Poland
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Sochaczew, 96-500, Poland

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Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-163, Poland

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Katowice, 40-146, Poland

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Chorzów, 41-500, Poland

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London, W12 0NN, United Kingdom

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London, SE5 8AZ, United Kingdom

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Cambridge, CB21 5EF, United Kingdom

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Wolverhampton, WV4 5HN, United Kingdom

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Sheffield, S5 7JT, United Kingdom

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Preston, Lancashire, PR2 9HT, United Kingdom

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Redruth, TR15 3QE, United Kingdom

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Stafford, ST16 3SR, United Kingdom
Local Institution - 2510
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Motherwell, ML1 4UF, United Kingdom

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Kropyvnytskyi, 25491, Ukraine

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Vinnytsia, Vinnytsia Oblast, 21037, Ukraine

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Lviv, Lviv Oblast, 79035, Ukraine

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Kyiv, Kyivska Oblast, 04080, Ukraine

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Dnipro, Dnipropetrovsk Oblast, 49115, Ukraine

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Smila, Cherkasy Oblast, 20708, Ukraine

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Hlevakha, Kyiv Oblast, 08631, Ukraine

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Poltava, Poltava Oblast, 36013, Ukraine

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Lviv, Lviv Oblast, 79035, Ukraine

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Skarzhyntsi, Khmelnytskyi Oblast, 32120, Ukraine

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Local Institution - 2565
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Kyiv, 01030, Ukraine

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Local Institution - 2566
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Hlevakha, Kyiv Oblast, 08631, Ukraine

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Local Institution - 2567
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Oleksandrivka, Odesa Oblast, 67513, Ukraine

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Local Institution - 2568
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Odesa, 65006, Ukraine

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Local Institution - 2569
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Lviv, Lviv Oblast, 79035, Ukraine

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Bonita Springs, Florida, 34134-4154, United States

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Local Institution - 2605
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Cypress, Texas, 77065, United States

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Long Beach, California, 90805, United States

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Morehead City, North Carolina, 28557, United States

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Chandler, Arizona, 85224, United States

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Local Institution - 2610
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Milwaukee, Wisconsin, 53226, United States

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Local Institution - 2613
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Pasadena, California, 91105, United States

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Local Institution - 2614
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San Diego, California, 92108, United States

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Local Institution - 2615
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Worcester, Massachusetts, 01608, United States

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Local Institution - 2617
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Blue Ash, Ohio, 45242, United States

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Local Institution - 2618
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Ann Arbor, Michigan, 48105, United States

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Local Institution - 2619
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Staten Island, New York, 10312, United States

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Local Institution - 2620
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Canoga Park, California, 91303, United States

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Local Institution - 2621
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Tampa, Florida, 33629, United States

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Local Institution - 2622
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Mesquite, Texas, 75150, United States

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Local Institution - 2623
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San Antonio, Texas, 78229, United States

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Local Institution - 2625
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Long Beach, California, 90040, United States

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Local Institution - 2626
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Hialeah, Florida, 33012, United States

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Local Institution - 2628
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Las Vegas, Nevada, 89030, United States

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Local Institution - 2629
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Hattiesburg, Mississippi, 39402, United States

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Local Institution - 2642
NOT_YET_RECRUITING

Long Beach, California, 90807, United States

Contact
National Hospital Organization Hizen Psychiatric Center
RECRUITING

Kanzaki-Gun Yoshinogari-Cho, Saga-ken, 842-0192, Japan

Contact Phone: •••-•••-••••
Nuovida Research Center
RECRUITING

Miami, Florida, 33186, United States

Contact Phone: •••-•••-••••
Okayama City General Medical Center Okayama City Hospital
RECRUITING

Okayama, 700-8557, Japan

Contact
Pantheon Clinical Research, LLC
RECRUITING

Bountiful, Utah, 84010, United States

Contact Phone: •••-•••-••••
Progressive Medical Research
RECRUITING

Port Orange, Florida, 32127, United States

Contact Phone: •••-•••-••••
Rainbow and Sea Hospital
RECRUITING

Karatsu-shi, Saga-ken, 847-0031, Japan

Contact Phone: •••-•••-••••
Seoul National University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 03080, South Korea

Contact Phone: •••-•••-••••
Surrey and Borders Partnership NHS Foundation Trust
RECRUITING

Chertsey, Surrey, KT16 9AU, United Kingdom

Contact Phone: •••-•••-••••
The Catholic University of Korea, Yeouido St.Mary's Hospital
RECRUITING

Seoul, 07345, South Korea

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

AGITATION ALZHEIMER DISEASE