Monthly HIV shot proves so effective trial stops early, all participants offered injection

NCT ID NCT03635788

Summary

This study tested if monthly injections of HIV medication work better than daily pills for people who have a hard time taking their medicine regularly. It involved 456 adults with HIV who had a history of poor medication adherence. The trial was so successful that an independent board recommended stopping the comparison early and offering the injection to all eligible participants.

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Contacts and locations

Locations

  • Alabama CRS

    Birmingham, Alabama, 35294, United States

  • Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS

    Boston, Massachusetts, 02115, United States

  • Case Clinical Research Site

    Cleveland, Ohio, 44106, United States

  • Chapel Hill CRS

    Chapel Hill, North Carolina, 27599, United States

  • Cincinnati Clinical Research Site

    Cincinnati, Ohio, 45219, United States

  • Columbia P&S CRS

    New York, New York, 10032-3732, United States

  • Greensboro CRS

    Greensboro, North Carolina, 27401, United States

  • Harbor-UCLA CRS

    Torrance, California, 90502, United States

  • Houston AIDS Research Team CRS

    Houston, Texas, 77030, United States

  • Jacobi Med. Ctr. Bronx NICHD CRS

    The Bronx, New York, 10461, United States

  • Johns Hopkins University CRS

    Baltimore, Maryland, 21205, United States

  • Massachusetts General Hospital CRS (MGH CRS)

    Boston, Massachusetts, 02114, United States

  • New Jersey Medical School Clinical Research Center CRS

    Newark, New Jersey, 07103, United States

  • Northwestern University CRS

    Chicago, Illinois, 60611, United States

  • Ohio State University CRS

    Columbus, Ohio, 43210, United States

  • Penn Therapeutics, CRS

    Philadelphia, Pennsylvania, 19104, United States

  • Puerto Rico AIDS Clinical Trials Unit CRS

    San Juan, 00935, Puerto Rico

  • Rush University CRS

    Chicago, Illinois, 60612, United States

  • SUNY Stony Brook NICHD CRS

    Stony Brook, New York, 11794, United States

  • The Miriam Hospital Clinical Research Site (TMH CRS) CRS

    Providence, Rhode Island, 02906, United States

  • The Ponce de Leon Center CRS

    Atlanta, Georgia, 30308-2012, United States

  • UCLA CARE Center CRS

    Los Angeles, California, 90035, United States

  • UCSD Antiviral Research Center CRS

    San Diego, California, 92103, United States

  • Ucsf Hiv/Aids Crs

    San Francisco, California, 94110, United States

  • Univ. of Florida Jacksonville NICHD CRS

    Jacksonville, Florida, 32209, United States

  • University of Colorado Hospital CRS

    Aurora, Colorado, 80045, United States

  • University of Pittsburgh CRS

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Southern California CRS

    Los Angeles, California, 90033-1079, United States

  • University of Washington AIDS CRS

    Seattle, Washington, 98104-9929, United States

  • Vanderbilt Therapeutics (VT) CRS

    Nashville, Tennessee, 37204, United States

  • Washington University Therapeutics (WT) CRS

    St Louis, Missouri, 63110-1010, United States

  • Weill Cornell Chelsea CRS

    New York, New York, 10010, United States

  • Weill Cornell Uptown CRS

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.