New hope for hard-to-treat lymphoma: targeted drug after chemo shows promise
NCT ID NCT05249959
First seen Jan 07, 2026 · Last updated May 16, 2026 · Updated 16 times
Summary
This study tests whether a targeted drug called loncastuximab tesirine can help people with mantle cell lymphoma whose cancer came back or didn't respond to previous treatments, including BTK inhibitors. About 49 adults will receive the drug after a short course of chemotherapy. The main goal is to see how long the cancer stays under control.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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ASST Spedali Civili di Brescia
RECRUITINGBrescia, Italy, 25123, Italy
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Dipartimento di Medicina Traslazionale e di Precisione - Policlinico Umberto I - Università "La Sapienza" Istituto Ematologia
RECRUITINGRoma, 00161, Italy
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Divisione di Ematologia - A.O. Ospedali Riuniti Villa Sofia-Cervello
RECRUITINGPalermo, 90146, Italy
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Divisione di Ematologia - IRCCS Policlinico S. Matteo di Pavia
RECRUITINGPavia, 27100, Italy
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Ematologia - Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova
RECRUITINGReggio Emilia, 42123, Italy
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Ematologia - Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
RECRUITINGMilan, 20133, Italy
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Ematologia - Ospedale Policlinico San Martino S.S.R.L. - IRCCS per l'Oncologia
RECRUITINGGenova, 16132, Italy
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Ematologia - Ospedale delle Croci
RECRUITINGRavenna, 48121, Italy
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S.C di Ematologia - Ospedale Ca Foncello
RECRUITINGTreviso, 31100, Italy
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S.C. Ematologia - A.S.O. "SS Antonio e Biagio e Cesare Arrigo"
RECRUITINGAlessandria, Italy
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S.C. Ematologia - ASST Grande Ospedale Metropolitano Niguarda
RECRUITINGMilan, 20162, Italy
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S.C. Ematologia Universitaria - A.O.U. Città della Salute e della Scienza di Torino
RECRUITINGTorino, 10126, Italy
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S.C. di Ematologia - A.O. S. Croce e Carle
RECRUITINGCuneo, 12100, Italy
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SC Ematologia - Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI)
RECRUITINGTrieste, 34121, Italy
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SCDU Ematologia - AOU Maggiore della Carità di Novara
RECRUITINGNovara, 28100, Italy
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U.O. Ematologia - AOU Integrata di Verona
RECRUITINGVerona, 37134, Italy
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U.O. Ematologia - Istituto Clinico Humanitas
RECRUITINGRozzano, 20089, Italy
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U.O. di Ematologia - Ospedale degli Infermi di Rimini
RECRUITINGRimini, 47923, Italy
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U.O.C Ematologia e Trapianto - A.O. C. Panico
RECRUITINGTricase, 73039, Italy
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UOC Ematologia Oncologica - Istituto Nazionale Tumori - IRCCS Fondazione G. Pascale
RECRUITINGNaples, 80131, Italy
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Unità funzionale di Ematologia - Azienda Ospedaliera Universitaria Careggi
RECRUITINGFlorence, 50141, Italy
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Conditions
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