Estrogen cream may help boys heal better after penis surgery

NCT ID NCT01370798

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 29 times

Summary

This study tested whether applying estrogen cream to the penis daily for two months before surgery could reduce complications like fistulas (abnormal openings) and wound separation in 244 boys with severe hypospadias, a birth defect where the urethra doesn't form properly. The boys were aged 9 to 36 months. The goal was to see if estrogen improves skin healing and lowers the need for repeat surgeries.

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Contacts and locations

Locations

  • Hôpital Mère-Enfant

    Nantes, 44093, France

  • Hôpital NECKER

    Paris, 75015, France

  • Hôpital Robert Debré

    Paris, 72015, France

  • Service de Chirurgie Pédiatrique Uro-génitale, Hopital femme Mere Enfant

    Bron, 69677, France

Conditions

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