Pinprick test: does injecting numbing medicine into different skin layers change how long it works?

NCT ID NCT07724418

First seen Jul 24, 2026 ยท Last updated Jul 24, 2026

Summary

This trial tests whether injecting local anesthetic into different layers of the skin on the forearm changes how long the numbing effect lasts. Healthy adults receive a small injection of lidocaine with epinephrine either just under the skin or into the skin itself. Researchers measure the time from when numbness begins to when sharp sensation returns.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
lidocaine with epinephrine
What this could lead to
If it works, this could help doctors choose the best injection depth for numbing during skin procedures.
What could go wrong
This is a small, early-phase study in healthy volunteers on the forearm, not on the face or other surgical sites, so results may not apply directly to real procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Weill Cornell Medicine

    New York, New York, 10065, United States