Knee cartilage regrowth injection shows promise in early trial
NCT ID NCT03275064
First seen May 05, 2026 · Last updated May 14, 2026 · Updated 1 time
Summary
This study tested an experimental drug called LNA043, given as a shot directly into the knee, to see if it can help regrow cartilage in people with knee cartilage damage or osteoarthritis. About 142 adults took part, receiving either the drug or a placebo. The main goals were to check safety and measure changes in cartilage quality and volume using MRI scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arizona Research
Phoenix, Arizona, 85053, United States
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Clinical Research of West Florida Inc
Tampa, Florida, 33606, United States
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LV Research
Las Vegas, Nevada, 89119, United States
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Midwest Orthopedics At Rush
Chicago, Illinois, 60612, United States
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Northern California Research
Sacramento, California, 95821, United States
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Novartis Investigative Site
Brno, Czech Republic, 66250, Czechia
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Novartis Investigative Site
Mladá Boleslav, Czech Republic, 29301, Czechia
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Novartis Investigative Site
Kladno, 272 59, Czechia
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Novartis Investigative Site
Kolín, 280 02, Czechia
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Novartis Investigative Site
Pardubice, 53002, Czechia
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Novartis Investigative Site
Prague, 190 00, Czechia
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Novartis Investigative Site
Aarhus N, 8200, Denmark
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Novartis Investigative Site
Hvidovre, 2650, Denmark
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Panax Clinical Research
Miami Lakes, Florida, 33014, United States
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Precision Clinical Research LLC
Sunrise, Florida, 33351, United States
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Scott A Hacker MD Medical Group d b a Horizon Clinical Res
La Mesa, California, 91942, United States
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St Lukes Intermountain Research Center
Boise, Idaho, 83702, United States
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Sundance Clinical Research LLC
St Louis, Missouri, 63141, United States
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Temple University
Philadelphia, Pennsylvania, 19140, United States
Conditions
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