New cancer drug enters early human testing

NCT ID NCT06187402

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase trial is testing an experimental drug called LM-24C5 in about 49 people with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it shows any signs of shrinking tumors. Participants receive the drug intravenously, and the study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LM-24C5 (an experimental drug given intravenously)

What this could lead to

If this works, it could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.

What could go wrong

This is a very early, small trial (49 people) focused on safety and dosing. The drug may not shrink tumors or could cause side effects. Success is far from guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University Melvan and Bren Simon Cancer Center

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

  • Mary Crowley Cancer Research Center

    NOT_YET_RECRUITING

    Dallas, Texas, 75230, United States

    Contact

  • Ocala Oncology

    RECRUITING

    Ocala, Florida, 34474, United States

    Contact

  • The Christ Hospital

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

  • University of Southern California (USC) - Norris Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90089, United States

    Contact

  • Virginia Cancer Specialists, P.C.

    NOT_YET_RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact