Heart defect kids get liver protection hope in new drug trial

NCT ID NCT03430583

Summary

This study tested whether a daily medication called udenafil could reduce liver stiffness in children with single ventricle heart disease who've had Fontan surgery. Researchers followed 88 children for one year, using special imaging scans to measure liver stiffness before and after treatment. The goal was to see if this medication could help protect the liver from damage caused by the heart condition.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Children's Mercy Hospital

    Kansas City, Kansas, 64108, United States

  • Children's Mercy Hospital Kansas City

    Kansas City, Missouri, 64108, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20008, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Nemours Cardiac Center/Alfred I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Primary Children's Medical Hospital/Dept. of Pediatric Cardiology

    Salt Lake City, Utah, 84113, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • The Hospital for Sick Children

    Toronto, Ontario, ON M5G 1X8, Canada

  • University of Michigan Congenital Heart Center

    Ann Arbor, Michigan, 48109-4204, United States

  • University of Nebraska Children's Hospital and Medical Center

    Omaha, Nebraska, 68114, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.