New scan could help spare healthy liver during cancer radiation

NCT ID NCT02967848

Ongoing Knowledge-focused Sponsor: Royal North Shore Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a special SPECT imaging scan called hepatobiliary scintigraphy to measure how radiotherapy changes liver function. Twenty adults with liver cancer will get the scan before and after radiation. The goal is to see if this method can show which parts of the liver are working well, so future treatments can avoid damaging healthy tissue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) - a special SPECT imaging scan
What this could lead to: If successful, this imaging technique could help doctors better plan radiotherapy to spare healthy liver tissue.
What could go wrong: This is a very small, early pilot study with only 20 participants. It is testing feasibility, not treatment effectiveness, so results may not change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CANCER, ADULT

Contacts and locations

Locations

Royal North Shore Hospital

St Leonards, New South Wales, 2065, Australia

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