New drugs target liver damage and drinking in groundbreaking trial
NCT ID NCT06409130
Summary
This study tested several new drug combinations to see if they could reduce liver scarring and alcohol use in people with alcohol-related liver disease. About 270 adults with a history of heavy drinking and early signs of liver damage received either the experimental drugs or a placebo for 39 weeks. The goal was to see if these medications could help control the disease by protecting the liver and reducing the urge to drink.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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"LANDA" Katarzyna Agata Landa
Krakow, 31-156, Poland
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"Laiko" General Hospital of Athens
Goudi/Athens, 11527, Greece
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'Ippokrateio' General Hospital of Thessaloniki
Thessaloniki, 54642, Greece
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AOU Careggi Firenze
Florence, Tuscany, 50134, Italy
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Aalborg Universitetshospital
Aalborg, 9000, Denmark
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Acibadem City Clinic UMHAT Tokuda EAD, Gastroenterology
Sofia, 1407, Bulgaria
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Akaicho Clinic
Chiba-shi, Chiba, 260-0804, Japan
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Albert Schweitzer Zkh, Dordwijk
Dordrecht, 3318 AT, Netherlands
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Amer. Rrsch Corp-TX Liver Inst
San Antonio, Texas, 78215, United States
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Arizona Liver Center
Tucson, Arizona, 85712, United States
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Austin Hospital
Heidelberg, Victoria, 3084, Australia
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Azienda Ospedaliera di Padova
Padua, 35128, Italy
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Baylor St. Luke's Medical Center
Houston, Texas, 77030, United States
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Boston Medical Center_Cary
Boston, Massachusetts, 02118, United States
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California Liver Research Institute
Pasadena, California, 91105, United States
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Centre Hospitalier Universitaire D'Angers
Angers, 49100, France
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Centre Hospitalier Universitaire de Lille-Hopital Claude Huriez
Lille, 59000, France
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Centre de Recherche Clinique Portes Du Sud
Vénissieux, 69200, France
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Centrum Medyczne Intercor Sp. z o.o.
Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-605, Poland
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Complejo Hospitalario de Pontevedra - Hospital de Montecelo
Pontevedra, Galicia, 36004, Spain
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Covenant Metabolic Specialists LLC
Fort Myers, Florida, 33912, United States
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Covenant Metabolic Specialists LLC
University Park, Florida, 34201, United States
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Ctr de Med Metab de Lanaudiere
Terrebonne, Quebec, J6X 4P7, Canada
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DCC XX - Sofia EOOD, Gastroenterology
Sofia, 1618, Bulgaria
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DSI Research,LLC
Springboro, Ohio, 45066, United States
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Del Sol Research Management, LLC
Tucson, Arizona, 85715, United States
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Digestive Health Research, TN
Hermitage, Tennessee, 37076, United States
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ETZ Elisabeth
Tilburg, 5022 GC, Netherlands
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Eastern Clinical Research Unit Box Hill
Box Hill, Victoria, 3128, Australia
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Erasmus MC
Rotterdam, 3015 GD, Netherlands
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Fiona Stanley Hospital - Hepatology
Murdoch, Western Australia, 6150, Australia
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Fondazione Evangelica Betania - UO Epatologia
Naples, 80147, Italy
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Fondazione Policlinico Universitario Agostino Gemelli IRCS
Roma, 00168, Italy
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GI Research Inst Foundation
Vancouver, British Columbia, V6Z 2K5, Canada
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Gastromed Sp. z o.o.
Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
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Heartlife Hospital_Liver internal medicine
Nakagamigun, Okinawa, 901-2492, Japan
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Herlev Hospital - Gastroenterology and Hepatology, Clinic 3
Herlev, 2730, Denmark
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Hospital Clinic i Provincial
Barcelona, Catalonia, 08036, Spain
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Hospital Clínico Universitario de Valladolid
Valladolid, España, 47003, Spain
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Hospital Universitario Marqués de Valdecilla
Santander, Cantabria, 39008, Spain
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Hospital Vall d'Hebron
Barcelona, 08035, Spain
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Houston Research Institute
Houston, Texas, 77079, United States
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Hvidovre Hospital - Gastroenheden
Hvidovre, 2650, Denmark
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ID Clinic Arkadiusz Pisula
Myslowice, Lesser Poland Voivodeship, 41-400, Poland
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IRCCS Ospedale Policlinico San Martino
Genova, 16132, Italy
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Ishikawa Prefectural Central Hospital_Gastroenterology
Kanazawa-shi, Ishikawa, 920-8530, Japan
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JCHO Hokkaido Hospital_Digestive Disease Center
Sapporo-shi, Hokkaido, 062-8618, Japan
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Jubilee Clinical Research, Inc.
Las Vegas, Nevada, 89106, United States
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Juntendo University Hospital, Gastroenterology
Bunkyo-ku, Tokyo, 113-8431, Japan
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Juntendo University Hospital_Gastroenterology
Bunkyo-ku, Tokyo, 113-8431, Japan
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Kansas Medical Clinic, PA
Topeka, Kansas, 66606, United States
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Krajská nemocice Liberec, a.s
Liberec, 460 01, Czechia
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Kumamoto Shinto General Hospital_Liver・Gastroenterology
Kumamoto-shi, Kumamoto, 862-8655, Japan
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Liver Specialists of Texas
Sugar Land, Texas, 77479, United States
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London Health Sciences Centre- University Hospital
London, Ontario, N6A5A5, Canada
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Louisiana Research Center, LLC
Shreveport, Louisiana, 71105, United States
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MHAT St. Ivan Rilski Gorna Oriahovitsa EOOD
Gorna Oryahovitsa, 5100, Bulgaria
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Mayo Clinic Rochester
Rochester, Minnesota, 55902, United States
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Medical Center Synexus Sofia EOOD
Sofia, 1784, Bulgaria
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Miguel Rebollar PA
Hialeah, Florida, 33012, United States
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Momentum Clinical Research Darlinghurst
Darlinghurst, New South Wales, 2010, Australia
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Naka Kinen Clinic_Internal medicine
Ibaraki, 311-0113, Japan
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Nepean Hospital
Kingswood, New South Wales, 2747, Australia
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Nihon University Itabashi Hospital_Division of Gastro.&Hepa.
Tokyo, 173-8610, Japan
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OM Research LLC
Lancaster, California, 93534, United States
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Odense University Hospital - FLASH - Centre for Liver Research
Odense C, 5000, Denmark
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Ogaki Municipal Hospital_Gastroenterology and Hepatology
Gifu, 503-8502, Japan
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Oita Cardiovascular Hospital_Gastroenterology
Oita-shi, Oita, 870-0837, Japan
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PANSTWOWY INSTYTUT MEDYCZNY MSWiA
Warsaw, Masovian Voivodeship, 02-507, Poland
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Pinnacle Clinical Research
San Antonio, Texas, 78229, United States
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Prof. Dr. Schiefke Ingolf, EUGASTRO GmbH
Leipzig, 04103, Germany
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Rush University Med. Cntr
Chicago, Illinois, 60612, United States
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Saiseikai Suita Hospital, Gastroenterology
Suita-shi, Osaka, 564-0013, Japan
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Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie
Krakow, Lesser Poland Voivodeship, 30-688, Poland
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Sonomed Sp. Z O.O.
Szczecin, West Pomeranian Voivodeship, 71-685, Poland
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South Texas Research Institute
Edinburg, Texas, 78539, United States
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St George Hospital
Kogarah, New South Wales, 2217, Australia
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St Vincent's Hospital Melbourne - Gastroenterology Department
Fitzroy, Victoria, 3065, Australia
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TDDA Specialty Research
Vaughan, Ontario, L4L 4Y7, Canada
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Texas Clinical Research Institute
Arlington, Texas, 76012, United States
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The Institute for Liver Health
Chandler, Arizona, 85224, United States
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The Liver Institute
Dallas, Texas, 75203, United States
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Toranomon Hospital, Hepatology
Minato-ku, Tokyo, 105-8470, Japan
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UF Hlth Jacksonville
Jacksonville, Florida, 32224, United States
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UMHAT Aleksandrovska EAD, Clinic of Endocrinology and Metabolic Diseases
Sofia, 1431, Bulgaria
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UMHAT Sveti Ivan Rilski EAD, Gastroenterology
Sofia, 1431, Bulgaria
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UPMC_Center for Liver Care
Pittsburgh, Pennsylvania, 15213, United States
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Uniklinik Schleswig-Holstein - Medizinischen Klinik I am Campus Lübeck
Lübeck, 23562, Germany
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Univ of Miami/Schiff Ctr
Miami, Florida, 33136, United States
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Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
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University Hospital of Athens ATTIKON
Athens, Attica, 12462, Greece
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University of Calgary Liver Unit-(HMRC)
Calgary, Alberta, T2N 4Z6, Canada
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University of Pennsylvania Hospital
Philadelphia, Pennsylvania, 19104, United States
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Universität des Saarlandes - Innere Med. II
Homburg, 66421, Germany
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Universitätsklinikum Leipzig - Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie und Pneumologie
Leipzig, 04103, Germany
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Universitätsklinikum Münster - Medizinische Klinik B
Münster, 48149, Germany
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Universitätsklinikum Würzburg - Zentrum für Innere Medizin (ZIM)
Würzburg, 97080, Germany
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Universitätsmedizin der JGU Mainz - Hepatologie
Mainz, 55131, Germany
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Uniwersytecki Szpital Kliniczny w Bialymstoku
Bialystok, Podlaskie Voivodeship, 15-540, Poland
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Velocity Clinical Res, Waco
Waco, Texas, 76710, United States
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Vseobecna Fakultni nemocnice v Praze
Prague, 128 08, Czechia
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Westmead Hospital - Storr Liver Centre
Westmead, New South Wales, 2145, Australia
Conditions
Explore the condition pages connected to this study.