New drugs target liver damage and drinking in groundbreaking trial

NCT ID NCT06409130

Summary

This study tested several new drug combinations to see if they could reduce liver scarring and alcohol use in people with alcohol-related liver disease. About 270 adults with a history of heavy drinking and early signs of liver damage received either the experimental drugs or a placebo for 39 weeks. The goal was to see if these medications could help control the disease by protecting the liver and reducing the urge to drink.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • "LANDA" Katarzyna Agata Landa

    Krakow, 31-156, Poland

  • "Laiko" General Hospital of Athens

    Goudi/Athens, 11527, Greece

  • 'Ippokrateio' General Hospital of Thessaloniki

    Thessaloniki, 54642, Greece

  • AOU Careggi Firenze

    Florence, Tuscany, 50134, Italy

  • Aalborg Universitetshospital

    Aalborg, 9000, Denmark

  • Acibadem City Clinic UMHAT Tokuda EAD, Gastroenterology

    Sofia, 1407, Bulgaria

  • Akaicho Clinic

    Chiba-shi, Chiba, 260-0804, Japan

  • Albert Schweitzer Zkh, Dordwijk

    Dordrecht, 3318 AT, Netherlands

  • Amer. Rrsch Corp-TX Liver Inst

    San Antonio, Texas, 78215, United States

  • Arizona Liver Center

    Tucson, Arizona, 85712, United States

  • Austin Hospital

    Heidelberg, Victoria, 3084, Australia

  • Azienda Ospedaliera di Padova

    Padua, 35128, Italy

  • Baylor St. Luke's Medical Center

    Houston, Texas, 77030, United States

  • Boston Medical Center_Cary

    Boston, Massachusetts, 02118, United States

  • California Liver Research Institute

    Pasadena, California, 91105, United States

  • Centre Hospitalier Universitaire D'Angers

    Angers, 49100, France

  • Centre Hospitalier Universitaire de Lille-Hopital Claude Huriez

    Lille, 59000, France

  • Centre de Recherche Clinique Portes Du Sud

    Vénissieux, 69200, France

  • Centrum Medyczne Intercor Sp. z o.o.

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-605, Poland

  • Complejo Hospitalario de Pontevedra - Hospital de Montecelo

    Pontevedra, Galicia, 36004, Spain

  • Covenant Metabolic Specialists LLC

    Fort Myers, Florida, 33912, United States

  • Covenant Metabolic Specialists LLC

    University Park, Florida, 34201, United States

  • Ctr de Med Metab de Lanaudiere

    Terrebonne, Quebec, J6X 4P7, Canada

  • DCC XX - Sofia EOOD, Gastroenterology

    Sofia, 1618, Bulgaria

  • DSI Research,LLC

    Springboro, Ohio, 45066, United States

  • Del Sol Research Management, LLC

    Tucson, Arizona, 85715, United States

  • Digestive Health Research, TN

    Hermitage, Tennessee, 37076, United States

  • ETZ Elisabeth

    Tilburg, 5022 GC, Netherlands

  • Eastern Clinical Research Unit Box Hill

    Box Hill, Victoria, 3128, Australia

  • Erasmus MC

    Rotterdam, 3015 GD, Netherlands

  • Fiona Stanley Hospital - Hepatology

    Murdoch, Western Australia, 6150, Australia

  • Fondazione Evangelica Betania - UO Epatologia

    Naples, 80147, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCS

    Roma, 00168, Italy

  • GI Research Inst Foundation

    Vancouver, British Columbia, V6Z 2K5, Canada

  • Gastromed Sp. z o.o.

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • Heartlife Hospital_Liver internal medicine

    Nakagamigun, Okinawa, 901-2492, Japan

  • Herlev Hospital - Gastroenterology and Hepatology, Clinic 3

    Herlev, 2730, Denmark

  • Hospital Clinic i Provincial

    Barcelona, Catalonia, 08036, Spain

  • Hospital Clínico Universitario de Valladolid

    Valladolid, España, 47003, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, Cantabria, 39008, Spain

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Houston Research Institute

    Houston, Texas, 77079, United States

  • Hvidovre Hospital - Gastroenheden

    Hvidovre, 2650, Denmark

  • ID Clinic Arkadiusz Pisula

    Myslowice, Lesser Poland Voivodeship, 41-400, Poland

  • IRCCS Ospedale Policlinico San Martino

    Genova, 16132, Italy

  • Ishikawa Prefectural Central Hospital_Gastroenterology

    Kanazawa-shi, Ishikawa, 920-8530, Japan

  • JCHO Hokkaido Hospital_Digestive Disease Center

    Sapporo-shi, Hokkaido, 062-8618, Japan

  • Jubilee Clinical Research, Inc.

    Las Vegas, Nevada, 89106, United States

  • Juntendo University Hospital, Gastroenterology

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Juntendo University Hospital_Gastroenterology

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Kansas Medical Clinic, PA

    Topeka, Kansas, 66606, United States

  • Krajská nemocice Liberec, a.s

    Liberec, 460 01, Czechia

  • Kumamoto Shinto General Hospital_Liver・Gastroenterology

    Kumamoto-shi, Kumamoto, 862-8655, Japan

  • Liver Specialists of Texas

    Sugar Land, Texas, 77479, United States

  • London Health Sciences Centre- University Hospital

    London, Ontario, N6A5A5, Canada

  • Louisiana Research Center, LLC

    Shreveport, Louisiana, 71105, United States

  • MHAT St. Ivan Rilski Gorna Oriahovitsa EOOD

    Gorna Oryahovitsa, 5100, Bulgaria

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55902, United States

  • Medical Center Synexus Sofia EOOD

    Sofia, 1784, Bulgaria

  • Miguel Rebollar PA

    Hialeah, Florida, 33012, United States

  • Momentum Clinical Research Darlinghurst

    Darlinghurst, New South Wales, 2010, Australia

  • Naka Kinen Clinic_Internal medicine

    Ibaraki, 311-0113, Japan

  • Nepean Hospital

    Kingswood, New South Wales, 2747, Australia

  • Nihon University Itabashi Hospital_Division of Gastro.&Hepa.

    Tokyo, 173-8610, Japan

  • OM Research LLC

    Lancaster, California, 93534, United States

  • Odense University Hospital - FLASH - Centre for Liver Research

    Odense C, 5000, Denmark

  • Ogaki Municipal Hospital_Gastroenterology and Hepatology

    Gifu, 503-8502, Japan

  • Oita Cardiovascular Hospital_Gastroenterology

    Oita-shi, Oita, 870-0837, Japan

  • PANSTWOWY INSTYTUT MEDYCZNY MSWiA

    Warsaw, Masovian Voivodeship, 02-507, Poland

  • Pinnacle Clinical Research

    San Antonio, Texas, 78229, United States

  • Prof. Dr. Schiefke Ingolf, EUGASTRO GmbH

    Leipzig, 04103, Germany

  • Rush University Med. Cntr

    Chicago, Illinois, 60612, United States

  • Saiseikai Suita Hospital, Gastroenterology

    Suita-shi, Osaka, 564-0013, Japan

  • Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie

    Krakow, Lesser Poland Voivodeship, 30-688, Poland

  • Sonomed Sp. Z O.O.

    Szczecin, West Pomeranian Voivodeship, 71-685, Poland

  • South Texas Research Institute

    Edinburg, Texas, 78539, United States

  • St George Hospital

    Kogarah, New South Wales, 2217, Australia

  • St Vincent's Hospital Melbourne - Gastroenterology Department

    Fitzroy, Victoria, 3065, Australia

  • TDDA Specialty Research

    Vaughan, Ontario, L4L 4Y7, Canada

  • Texas Clinical Research Institute

    Arlington, Texas, 76012, United States

  • The Institute for Liver Health

    Chandler, Arizona, 85224, United States

  • The Liver Institute

    Dallas, Texas, 75203, United States

  • Toranomon Hospital, Hepatology

    Minato-ku, Tokyo, 105-8470, Japan

  • UF Hlth Jacksonville

    Jacksonville, Florida, 32224, United States

  • UMHAT Aleksandrovska EAD, Clinic of Endocrinology and Metabolic Diseases

    Sofia, 1431, Bulgaria

  • UMHAT Sveti Ivan Rilski EAD, Gastroenterology

    Sofia, 1431, Bulgaria

  • UPMC_Center for Liver Care

    Pittsburgh, Pennsylvania, 15213, United States

  • Uniklinik Schleswig-Holstein - Medizinischen Klinik I am Campus Lübeck

    Lübeck, 23562, Germany

  • Univ of Miami/Schiff Ctr

    Miami, Florida, 33136, United States

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • University Hospital of Athens ATTIKON

    Athens, Attica, 12462, Greece

  • University of Calgary Liver Unit-(HMRC)

    Calgary, Alberta, T2N 4Z6, Canada

  • University of Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19104, United States

  • Universität des Saarlandes - Innere Med. II

    Homburg, 66421, Germany

  • Universitätsklinikum Leipzig - Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie und Pneumologie

    Leipzig, 04103, Germany

  • Universitätsklinikum Münster - Medizinische Klinik B

    Münster, 48149, Germany

  • Universitätsklinikum Würzburg - Zentrum für Innere Medizin (ZIM)

    Würzburg, 97080, Germany

  • Universitätsmedizin der JGU Mainz - Hepatologie

    Mainz, 55131, Germany

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, Podlaskie Voivodeship, 15-540, Poland

  • Velocity Clinical Res, Waco

    Waco, Texas, 76710, United States

  • Vseobecna Fakultni nemocnice v Praze

    Prague, 128 08, Czechia

  • Westmead Hospital - Storr Liver Centre

    Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.