New drug trial aims to keep liver disease patients out of the hospital

NCT ID NCT05297448

Ongoing Disease control Sponsor: Bausch Health Americas, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a medication called rifaximin can delay the first serious brain complication in people with advanced liver disease (cirrhosis) who have controlled fluid buildup in their abdomen. About 466 participants will receive either the medication or a placebo (inactive pill) to see which group goes longer without needing medical care for these brain issues or dying. The goal is to help people with cirrhosis stay healthier and avoid hospital visits.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Bausch Site 350

Mangaluru, 575003, India
Bausch Site 351

Sūrat, 395009, India
Bausch Site 352

Belagavi, 590010, India
Bausch Site 354

Nashik, 422005, India
Bausch Site 356

Nagpur, 440010, India
Bausch Site 361

Secunderabad, 500003, India
Bausch Site 400

Harrisburg, Pennsylvania, 17110, United States
Bausch Site 401

The Bronx, New York, 10467, United States
Bausch Site 402

Burlington, Vermont, 05401, United States
Bausch Site 403

Springboro, Ohio, 45066, United States
Bausch Site 404

Roanoke, Virginia, 24014, United States
Bausch Site 405

Orange, California, 92868, United States
Bausch Site 406

Dallas, Texas, 75390, United States
Bausch Site 407

Port Orange, Florida, 32127, United States
Bausch Site 409

Waco, Texas, 76712, United States
Bausch Site 410

Dayton, Ohio, 45414, United States
Bausch Site 411

Sparta, New Jersey, 07871, United States
Bausch Site 413

New Orleans, Louisiana, 70125, United States
Bausch Site 414

Los Angeles, California, 90067, United States
Bausch Site 415

Coronado, California, 92118, United States
Bausch Site 416

Wichita Falls, Texas, 76301, United States
Bausch Site 418

Hialeah, Florida, 33013, United States
Bausch Site 421

Orange City, Florida, 32763, United States
Bausch Site 422

Smithfield, North Carolina, 27577, United States
Bausch Site 423

Chattanooga, Tennessee, 37421, United States
Bausch Site 424

Richmond, Virginia, 23226, United States
Bausch Site 425

Doral, Florida, 33122, United States
Bausch Site 427

Asheville, North Carolina, 28801, United States
Bausch Site 428

Miami, Florida, 33126, United States
Bausch Site 429

Zephyrhills, Florida, 33542, United States
Bausch Site 431/443

Ocala, Florida, 34471, United States
Bausch Site 434

Chattanooga, Tennessee, 37421, United States
Bausch Site 435

Miami, Florida, 33186, United States
Bausch Site 436

East Syracuse, New York, 13057, United States
Bausch Site 437

Houston, Texas, 77074, United States
Bausch Site 440

Guaynabo, 00966, Puerto Rico
Bausch Site 442

Shreveport, Louisiana, 71105, United States
Bausch Site 445

Chandler, Arizona, 85224, United States
Bausch Site 446

Ocoee, Florida, 34761, United States
Bausch Site 447

Humble, Texas, 77346, United States
Bausch Site 448

San Marcos, Texas, 78130, United States
Bausch Site 449

Hialeah, Florida, 33012, United States
Bausch Site 450

Ocala, Florida, 34471, United States
Bausch Site 452

Miami Lakes, Florida, 33016, United States
Bausch Site 453

Sun City, Arizona, 85351, United States
Bausch Site 454

Wellington, Florida, 33467, United States
Bausch Site 455

Toms River, New Jersey, 08755, United States
Bausch Site 456

Miami, Florida, 33175, United States
Bausch Site 457

Lafayette, Louisiana, 70503, United States
Bausch Site 458

Miami, Florida, 33176, United States
Bausch Site 460

Jefferson City, Missouri, 65109, United States
Bausch Site 463

Flowood, Mississippi, 39232, United States
Bausch Site 466

West Des Moines, Iowa, 50266, United States
Bausch Site 468

Hollywood, Florida, 33024, United States
Bausch Site 470

Miami, Florida, 33134, United States
Bausch Site 472

Westlake, Ohio, 44145, United States
Bausch Site 475

Gurnee, Illinois, 60031, United States
Bausch Site 479

Miami, Florida, 33125, United States
Bausch Site 480

Summerville, South Carolina, 29486, United States
Bausch Site 482

Valencia, California, 91355, United States
Bausch Site 484

Providence, Rhode Island, 02905, United States
Bausch Site 486

Miami, Florida, 33144, United States
Bausch Site 488

Metairie, Louisiana, 70006, United States
Bausch Site 490

Richmond, Virginia, 23229, United States
Bausch Site 494

Monroe, North Carolina, 28112, United States
Bausch Site 495

Miami, Florida, 23229, United States
Bausch Site 519

Denison, Texas, 75929, United States
Bausch Site 524

Topeka, Kansas, 66606, United States
Bausch Site 531

Marrero, Louisiana, 70072, United States
Bausch Site 537

Palmetto Bay, Florida, 33157, United States
Bausch Site 543

Miami, Florida, 33032, United States
Bausch Site 550

Bakersfield, California, 93309, United States
Bausch Site 552

Miami, Florida, 33165, United States
Bausch Site 558

Hialeah, Florida, 33012, United States
Bausch Site 559

Norfolk, Virginia, 23502, United States
Bausch Site 575

Colorado Springs, Colorado, 80907, United States
Bausch Site 576

Philadelphia, Pennsylvania, 19104, United States
Bausch Site 577

Macon, Georgia, 31201, United States
Bausch Site 579

Hermitage, Tennessee, 37076, United States
Bausch Site 580

Liberty Township, Ohio, 45044, United States
Bausch Site 581

Allentown, Pennsylvania, 18104, United States
Bausch Site 582

Lancaster, California, 93534, United States
Bausch Site 583

Greenbelt, Maryland, 20770, United States
Bausch Site 585

Covina, California, 91722, United States
Bausch Site 585

Covina, California, 91723, United States
Bausch Site 587

Tucson, Arizona, 85715, United States
Bausch Site 588

South Bend, Indiana, 46635, United States
Bausch Site 589

San Juan, 00907, Puerto Rico
Bausch Site 590

Long Beach, California, 90808, United States
Bausch Site 591

Homewood, Alabama, 35209, United States
Bausch Site 592

Fresno, California, 93720, United States
Bausch Site 594

Miami, Florida, 33165, United States
Bausch Site 595

Richmond, Virginia, 23236, United States
Bausch Site 596

Orlando, Florida, 32808, United States
Bausch Site 597

Freehold, New Jersey, 07728, United States
Bausch Site 598

Florham Park, New Jersey, 07932, United States
Bausch Site 599

Columbia, South Carolina, 29204, United States
Bausch Site 600

Union City, Tennessee, 38261, United States
Bausch Site 605

Québec, G1V 4T3, Canada
Bausch Site 709

Camperdown, New South Wales, 2050, Australia
Bausch Site 710

Westmead, New South Wales, 2145, Australia
Bausch Site 737

Berlin, 10117, Germany
Bausch Site 751

Busan, 49241, South Korea
Bausch Site 752

Seoul, 03080, South Korea
Bausch Site 753

Seoul, 06351, South Korea
Bausch Site 754

Gyeongsang, 50612, South Korea
Bausch Site 755

Seoul, 08308, South Korea
Bausch Site 757

Seoul, 013722, South Korea
Bausch Site 758

Goyang-si, 10408, South Korea
Bausch Site 759

Busan, 47392, South Korea
Bausch Site 760

Seoul, 06273, South Korea
Bausch Site 761

Yongin-si, 16995, South Korea
Bausch Site 762

Seoul, 03312, South Korea
Bausch Site 763

Daejeon, 34943, South Korea
Bausch Site 764

Daegu, 42601, South Korea
Bausch Site 765

Gyeonggi-do, 15355, South Korea
Bausch Site 766

Seoul, 01830, South Korea
Bausch Site 767

Seoul, 06591, South Korea
Bausch Site 768

Gangwon-do, 26426, South Korea
Bausch Site 769

Daegu, 41944, South Korea
Bausch Site 770

Seongnam-si, 13496, South Korea
Bausch Site 776

Grafton, 1023, New Zealand
Bausch Site 778

Hamilton, 3240, New Zealand
Bausch Site 779

Christchurch, 8011, New Zealand
Bausch Site 801

Paris, 75013, France
Bausch Site 802

Clermont-Ferrand, 63003, France
Bausch Site 803

Toulouse, 31059, France
Bausch Site 804

Angers, 49100, France
Bausch Site 805

Lyon, 69004, France
Bausch Site 807

Nice, 06200, France
Bausch Site 808

Limoges, 87042, France
Bausch Site 809

Pessac, 33604, France
Bausch Site 810

Besançon, 25000, France
Bausch Site 811

Villejuif, 94804, France
Bausch Site 813

Vandœuvre-lès-Nancy, 54500, France
Bausch Site 815

Rennes, 35033, France
Bausch Site 817

Paris, 75014, France
Bausch Site 818

Belfort, 90015, France
Bausch Site 856

Debrecen, 4032, Hungary
Bausch Site 859

Budapest, 1111, Hungary
Bausch Site 879

Rozzano, 20089, Italy
Bausch Site 881

Milan, 20132, Italy
Bausch Site 882

Palermo, 90127, Italy
Bausch Site 883

Naples, 80131, Italy
Bausch Site 884

Novara, 28100, Italy
Bausch Site 901

Mysłowice, 41-400, Poland
Bausch Site 902

Bydgoszcz, 85-605, Poland
Bausch Site 903

Staszów, 28-200, Poland
Bausch Site 904

Katowice, 40-752, Poland
Bausch Site 906

Wroclaw, 51-162, Poland
Bausch Site 908

Wroclaw, 50-220, Poland
Bausch Site 909

Krakow, 30-721, Poland
Bausch Site 927

Zaragoza, 50009, Spain
Bausch Site 928

Málaga, 29010, Spain
Bausch Site 931

Barcelona, 08035, Spain
Bausch Site 933

Valencia, 46010, Spain
Bausch Site 935

Valencia, 46014, Spain
Bausch Site 936

Pontevedra, 36164, Spain
Bausch Site 937

Madrid, 28034, Spain
Bausch Site 941

Dundee, DD1 9SY, United Kingdom
Bausch Site 942

Plymouth, PL6 8DH, United Kingdom
Bausch Site 945

Nottingham, NG7 2UH, United Kingdom
Bausch Site 946

Liverpool, L9 7AL, United Kingdom
Bausch Site 947

Hull, HU3 2JZ, United Kingdom
Bausch Site 966

Stara Zagora, 6000, Bulgaria
Bausch Site 967

Sofia, 1431, Bulgaria
Bausch Site 968

Sofia, 1606, Bulgaria
Bausch Site 969

Sliven, 8800, Bulgaria
Bausch Site 970

Ulaanbaatar, 14230, Mongolia
Bausch Site 972

Antwerp, 2650, Belgium
Bausch Site 973

Ghent, 9000, Belgium
Bausch Site 974

Liège, 4000, Belgium
Bausch Site 975

Mechelen, 2800, Belgium
Bausch Site 976

Kortrijk, 8500, Belgium
Bausch Site 978

Genk, 3600, Belgium
Bausch Site 982

Rousse, 7013, Bulgaria
Bausch Site 984

Sofia, 1618, Bulgaria
Bausch Site Albany Medical Clinic

Toronto, Ontario, M3M 0A9, Canada
Bausch Site Barrie GI Associates

Barrie, Ontario, L4M 7G1, Canada
Bausch Site Brampton Civic Hospital

Brampton, Ontario, L6R 3J7, Canada
Bausch Site Clinique Medicale L'Actuel

Montreal, Quebec, H2L 4P9, Canada
Bausch Site G.I.R.I. GI Research Institute

Vancouver, British Columbia, V6Z 2K5, Canada
Bausch Site Heritage Medical Research Clinic

Calgary, Alberta, T2N 4Z6, Canada
Bausch Site McMaster University Medical Centre - Hamilton Health Services

Hamilton, Ontario, L8V 1C3, Canada
Bausch Site Toronto General Hospital

Toronto, Ontario, M5G 1N8, Canada
Bausch Site University of Alberta Hospital

Edmonton, Alberta, T6G 2B7, Canada
Bausch Site: CHUM Centre de Recherche

Montreal, Quebec, HSX 0A9, Canada
Bausch Site: Pharmaceutical Integrated Research Corporation

Waterloo, Ontario, N2J 1C4, Canada

Conditions

Explore the condition pages connected to this study.

HEPATIC ENCEPHALOPATHY