Starving cancer cells: new drug aims to boost effectiveness of common liver cancer procedure

NCT ID NCT05842174

Summary

This study is testing if adding a drug called hydroxychloroquine to a standard liver cancer treatment (TACE) makes it work better. TACE works by cutting off a tumor's blood supply to starve it. Researchers think cancer cells survive this starvation by 'eating' themselves, a process called autophagy. They want to see if hydroxychloroquine, which blocks this process, helps kill more cancer cells and keeps the tumor from coming back. The trial will enroll about 93 adults with intermediate-stage liver cancer who are not candidates for surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

    Philadelphia, Pennsylvania, 19104-4551, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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