Could your own immune cells fight liver cancer? new trial aims to find out
NCT ID NCT03942328
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new approach for people with advanced liver cancer that cannot be surgically removed. Participants receive radiation followed by an injection of their own specially trained immune cells (dendritic cells), a pneumonia vaccine to boost immunity, and immunotherapy drugs. The goal is to see if this combination is safe and can help the body attack the tumor. The trial is currently recruiting 85 adults with specific types of liver cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous dendritic cells (immune cells grown from the patient's own blood), Prevnar (pneumonia vaccine), atezolizumab, durvalumab, bevacizumab
What this could lead to
If it works, this could point toward a new treatment option for people with liver cancer that cannot be removed by surgery.
What could go wrong
This is an early-phase trial with only 85 participants, so results may not apply to everyone. The combination therapy may cause significant side effects or fail to improve outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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