Major trial tests if immunotherapy boosts standard liver cancer treatment

NCT ID NCT03778957

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This global study is testing whether adding immunotherapy drugs (durvalumab with or without bevacizumab) to the standard liver cancer treatment called TACE helps patients live longer without their cancer getting worse. The trial involves 724 patients with liver cancer that cannot be cured by surgery but can be treated with TACE. Researchers want to see if the drug combinations improve survival and quality of life compared to TACE alone.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Costa Mesa, California, 92627, United States
Research Site

La Jolla, California, 92093-0698, United States
Research Site

Orange, California, 92868, United States
Research Site

Washington D.C., District of Columbia, 20007, United States
Research Site

Jacksonville, Florida, 32224, United States
Research Site

Miami, Florida, 33136, United States
Research Site

Honolulu, Hawaii, 96819, United States
Research Site

Chicago, Illinois, 60612, United States
Research Site

Shreveport, Louisiana, 71103, United States
Research Site

Detroit, Michigan, 48201, United States
Research Site

Rochester, Minnesota, 55905-0001, United States
Research Site

St Louis, Missouri, 63110, United States
Research Site

Stony Brook, New York, 11794, United States
Research Site

Charlotte, North Carolina, 28204, United States
Research Site

Cleveland, Ohio, 44106, United States
Research Site

Portland, Oregon, 97213, United States
Research Site

Pittsburgh, Pennsylvania, 15212, United States
Research Site

Sioux Falls, South Dakota, 57105, United States
Research Site

Memphis, Tennessee, 38104, United States
Research Site

Dallas, Texas, 75216, United States
Research Site

Dallas, Texas, 75235, United States
Research Site

Houston, Texas, 77030, United States
Research Site

Houston, Texas, 77090, United States
Research Site

Milwaukee, Wisconsin, 53226, United States
Research Site

Benowa, 4217, Australia
Research Site

Box Hill, 3128, Australia
Research Site

Camperdown, 2050, Australia
Research Site

Clayton, 3168, Australia
Research Site

Herston, 4029, Australia
Research Site

Liverpool, 2170, Australia
Research Site

Melbourne, 3004, Australia
Research Site

Barretos, 14784-400, Brazil
Research Site

Florianópolis, 88034-000, Brazil
Research Site

Porto Alegre, 90020-090, Brazil
Research Site

Porto Alegre, 90035-003, Brazil
Research Site

Porto Alegre, 91350-200, Brazil
Research Site

Rio de Janeiro, 20231-050, Brazil
Research Site

Santa Maria, 97015-450, Brazil
Research Site

São José do Rio Preto, 15090-000, Brazil
Research Site

São Paulo, 01323-903, Brazil
Research Site

Vitória, 29043-272, Brazil
Research Site

Ottawa, Ontario, K1H 8L6, Canada
Research Site

Toronto, Ontario, M4N 3M5, Canada
Research Site

Toronto, Ontario, M5G 2M9, Canada
Research Site

Montreal, Quebec, H2X 3E4, Canada
Research Site

Montreal, Quebec, H4A 3J1, Canada
Research Site

Beijing, 100021, China
Research Site

Beijing, 100036, China
Research Site

Beijing, 100069, China
Research Site

Beijing, 100730, China
Research Site

Changchun, 130021, China
Research Site

Changsha, 410013, China
Research Site

Chengdu, 610041, China
Research Site

Fuzhou, 350005, China
Research Site

Fuzhou, 350025, China
Research Site

Guangzhou, 510060, China
Research Site

Guangzhou, 510080, China
Research Site

Guangzhou, 510515, China
Research Site

Hangzhou, 310022, China
Research Site

Harbin, 150081, China
Research Site

Hefei, 230001, China
Research Site

Nanchang, 330006, China
Research Site

Nanjing, 210002, China
Research Site

Nanjing, 210009, China
Research Site

Nantong, 226361, China
Research Site

Neijiang, 641100, China
Research Site

Shanghai, 200032, China
Research Site

Shanghai, 201508, China
Research Site

Shenyang, 110001, China
Research Site

Shenzhen, 518053, China
Research Site

Tianjin, 300170, China
Research Site

Wuhan, 430010, China
Research Site

Wuhan, 430079, China
Research Site

Xi'an, 710061, China
Research Site

Zhengzhou, 450008, China
Research Site

Zhuhai, 519000, China
Research Site

Bobigny, 93000, France
Research Site

Clichy, 92210, France
Research Site

Grenoble, 38043, France
Research Site

Montpellier, 34295, France
Research Site

Nice, 06202, France
Research Site

Paris, 75651, France
Research Site

Pessac, 33604, France
Research Site

Toulouse, 31059, France
Research Site

Vandœuvre-lès-Nancy, 54511, France
Research Site

Hong Kong, 999077, Hong Kong
Research Site

Shatin, 00000, Hong Kong
Research Site

Bangalore, 560068, India
Research Site

Bengaluru, 560076, India
Research Site

Hyderabad, 500004, India
Research Site

Kolkata, 700054, India
Research Site

Kolkata, 700160, India
Research Site

Madurai, 625107, India
Research Site

Mumbai, 400 012, India
Research Site

Nashik, 422002, India
Research Site

Pune, 411004, India
Research Site

Surat, 395002, India
Research Site

Vijayawada, 520002, India
Research Site

Visakhapatnam, 530017, India
Research Site

Arezzo, 52100, Italy
Research Site

Brescia, 25100, Italy
Research Site

Milan, 20132, Italy
Research Site

Milan, 20133, Italy
Research Site

Pisa, 56124, Italy
Research Site

Bunkyō City, 113-8655, Japan
Research Site

Chiba, 260-8677, Japan
Research Site

Chūōku, 104-0045, Japan
Research Site

Fukuoka, 810-8563, Japan
Research Site

Hiroshima, 734-8551, Japan
Research Site

Kurume-shi, 830-0011, Japan
Research Site

Musashino-shi, 180-8610, Japan
Research Site

Nagoya, 464-8681, Japan
Research Site

Okayama, 700-8558, Japan
Research Site

Osaka, 534-0021, Japan
Research Site

Osaka, 545-8586, Japan
Research Site

Osakasayama-shi, 589-8511, Japan
Research Site

Sapporo, 006-8555, Japan
Research Site

Shiwa-gun, 028-3695, Japan
Research Site

Tsu, 514-8507, Japan
Research Site

Yokohama, 241-8515, Japan
Research Site

Alc. Cuauhtémoc, 06100, Mexico
Research Site

Culiacán, 80230, Mexico
Research Site

Guadalajara, 44280, Mexico
Research Site

Mérida, 97134, Mexico
Research Site

México, 14080, Mexico
Research Site

Monterrey, 64460, Mexico
Research Site

Monterrey, 64710, Mexico
Research Site

Tuxtla Gutiérrez, 29090, Mexico
Research Site

Barnaul, 656049, Russia
Research Site

Kazan', 420029, Russia
Research Site

Moscow, 115478, Russia
Research Site

Novosibirsk, 630007, Russia
Research Site

Obninsk, 249031, Russia
Research Site

Saint Petersburg, 197758, Russia
Research Site

Yekaterinburg, 620905, Russia
Research Site

Singapore, 168583, Singapore
Research Site

Busan, 49241, South Korea
Research Site

Daegu, 41944, South Korea
Research Site

Goyang-si, 10408, South Korea
Research Site

Seoul, 03080, South Korea
Research Site

Seoul, 03722, South Korea
Research Site

Seoul, 05505, South Korea
Research Site

Seoul, 06351, South Korea
Research Site

Córdoba, 14004, Spain
Research Site

Madrid, 28007, Spain
Research Site

Pamplona, 31008, Spain
Research Site

San Sebastián(Guipuzcoa), 20014, Spain
Research Site

Kaohsiung City, 833, Taiwan
Research Site

Liou Ying Township, 736, Taiwan
Research Site

Taichung, 404, Taiwan
Research Site

Taichung, 40705, Taiwan
Research Site

Tainan, 704, Taiwan
Research Site

Taipei, 10002, Taiwan
Research Site

Taipei, 11217, Taiwan
Research Site

Taoyuan, 333, Taiwan
Research Site

Bangkok, 10210, Thailand
Research Site

Bangkok, 10300, Thailand
Research Site

Bangkok, 10400, Thailand
Research Site

Chiang Mai, 50200, Thailand
Research Site

Hat Yai, 90110, Thailand
Research Site

Khon Kaen, 40002, Thailand
Research Site

Phisanulok, 65000, Thailand
Research Site

Hanoi, 100000, Vietnam
Research Site

Hanoi, 123, Vietnam
Research Site

Ho Chi Minh City, 700000, Vietnam
Research Site

Ho Chi Minh City, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

HEPATOCELLULAR CARCINOMA