New hope for liver cancer: triple-drug combo enters final testing

NCT ID NCT06921785

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests whether a new drug called rilvegostomig, combined with standard treatments, helps people with advanced liver cancer live longer. About 1220 adults whose cancer cannot be removed or treated with local therapies will receive either the new combination or the current standard treatment. The goal is to see if the new approach improves survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

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Phoenix, Arizona, 85054, United States
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Tucson, Arizona, 85719, United States
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Palo Alto, California, 94304, United States
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Santa Monica, California, 90404, United States
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New Haven, Connecticut, 06511, United States
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Newark, Delaware, 19713, United States
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Jacksonville, Florida, 32224, United States
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Atlanta, Georgia, 30318, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60637, United States
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Indianapolis, Indiana, 46202, United States
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Shreveport, Louisiana, 71103, United States
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Detroit, Michigan, 48202, United States
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Grand Rapids, Michigan, 49503, United States
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Rochester, Minnesota, 55905, United States
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New Brunswick, New Jersey, 08901, United States
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New York, New York, 10029, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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Cleveland, Ohio, 44195, United States
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Philadelphia, Pennsylvania, 19107, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Austin, Texas, 78705, United States
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Dallas, Texas, 75390, United States
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El Paso, Texas, 79902, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78240, United States
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Tyler, Texas, 75702, United States
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Arlington, Virginia, 22201, United States
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Salem, Virginia, 24153, United States
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Seattle, Washington, 98109, United States
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Milwaukee, Wisconsin, 53226, United States
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Auchenflower, 4066, Australia
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Camperdown, 2050, Australia
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Clayton, 3168, Australia
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Heidelberg, 3084, Australia
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Barretos, 14784-400, Brazil
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Porto Alegre, 91350-200, Brazil
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Santa Maria, 97015-450, Brazil
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São Paulo, 04014-002, Brazil
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São Paulo, 05652-9000, Brazil
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Vitória, 29043-272, Brazil
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Edmonton, Alberta, T6G 1Z2, Canada
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Halifax, Nova Scotia, B3H 1V7, Canada
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Barrie, Ontario, L4M 6M2, Canada
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Brampton, Ontario, L6R 3J7, Canada
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Cambridge, Ontario, N1R 3G2, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G 1X6, Canada
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Montreal, Quebec, H2X 0A9, Canada
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Québec, Quebec, G1J 1Z4, Canada
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Beijing, 100034, China
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Beijing, 100142, China
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Beijing, CN-100730, China
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Changchun, 130021, China
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Changsha, 410013, China
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Chengdu, 610041, China
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Chengdu, 610041, China
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Chifeng, 024000, China
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Chongqing, 400010, China
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Deyang, 618000, China
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Fuzhou, 350005, China
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Guangzhou, 510060, China
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Guangzhou, 510515, China
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Guiyang, 550002, China
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Harbin, 150081, China
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Hefei, 230022, China
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Hohhot, 010020, China
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Kunming, 650118, China
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Linyi, 276000, China
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Lishui, 323000, China
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Luoyang, 471000, China
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Nanchang, 330008, China
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Nanchang, 330029, China
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Nanjing, 210029, China
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Nanning, 530021, China
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Nantong, 226361, China
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Neijiang, 641100, China
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Shandong, China
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Shanghai, 201114, China
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Shenyang, 110004, China
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Shenyang, 110042, China
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Weifang, 261000, China
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Wenzhou, 325000, China
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Wuhan, 430079, China
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Xi'an, 710100, China
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Zhengzhou, 450008, China
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Clichy, 92118, France
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Lille, 59000, France
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Lyon, 69317, France
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Nantes, 44093, France
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Nice, 06200, France
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Pessac, 33604, France
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Rennes, 35000, France
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Toulouse, 31059, France
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Aachen, 52074, Germany
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Berlin, 13353, Germany
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Bonn, 53127, Germany
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Dortmund, 44137, Germany
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Dresden, 01307, Germany
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Essen, 45122, Germany
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Frankfurt, 60488, Germany
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Frankfurt, 60590, Germany
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Göttingen, 37075, Germany
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Hamburg, 20246, Germany
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Hanover, 30623, Germany
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Leipzig, 4103, Germany
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Lübeck, 23538, Germany
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Magdeburg, 39120, Germany
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Moers, 47441, Germany
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München, 81377, Germany
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Regensburg, 93053, Germany
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Ulm, 89081, Germany
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Hong Kong, 999077, Hong Kong
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Shatin, 00000, Hong Kong
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Ahmedabad, 380058, India
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Bangalore, 560027, India
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Binnāguri, 734015, India
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Dehradun, 248016, India
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Delhi, 110029, India
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Hyderabad, 500032, India
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Mumbai, 400012, India
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Nashik, 422011, India
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Vadodara, 391760, India
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Bologna, 40138, Italy
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Milan, 20132, Italy
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Milan, 20162, Italy
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Palermo, 90127, Italy
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Perugia, 06132, Italy
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Pisa, 56126, Italy
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Roma, 00168, Italy
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Rozzano, 20089, Italy
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Bunkyō City, 113-8655, Japan
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Chiba, 260-8677, Japan
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Fukuoka, 811-1395, Japan
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Hiroshima, 734-8530, Japan
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Hiroshima, 734-8551, Japan
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Iizuka-shi, 820-8505, Japan
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Kashiwa, 227-8577, Japan
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Kita-gun, 761-0793, Japan
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Kobe, 650-0017, Japan
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Kōtoku, 135-8550, Japan
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Kumamoto, 860-8556, Japan
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Kurume-shi, 830-0011, Japan
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Kyoto, 602-8566, Japan
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Matsuyama, 790-0024, Japan
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Mitaka-shi, 181-8611, Japan
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Morioka, 028-3695, Japan
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Musashino-shi, 180-8610, Japan
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Nagoya, 464-8681, Japan
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Okayama, 700-8558, Japan
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Osaka, 541-8567, Japan
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Osakasayama-shi, 589-8511, Japan
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Saga, 849-8501, Japan
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Sapporo, 006-8555, Japan
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Sendai, 981-0914, Japan
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Suita-shi, 565-0871, Japan
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Tokyo, 104-0045, Japan
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Toyoake-shi, 470-1192, Japan
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Tsu, 514-8507, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 241-8515, Japan
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Amsterdam, 1081HV, Netherlands
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Groningen, 9700 RB, Netherlands
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Maastricht, 6229 HX, Netherlands
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Rotterdam, 3015 GD, Netherlands
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Utrecht, 3584 CX, Netherlands
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Gdansk, 80-214, Poland
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Koszalin, 75-581, Poland
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Lublin, 20-090, Poland
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Olsztyn, 10-228, Poland
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Warsaw, 02-034, Poland
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Busan, 48108, South Korea
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Goyang-si, 410-769, South Korea
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Gyeonggi-do, 13620, South Korea
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Seongnam-si, 463-712, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 5505, South Korea
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Barcelona, 08035, Spain
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Barcelona, 08036, Spain
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Madrid, 28007, Spain
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Madrid, 28027, Spain
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Madrid, 28040, Spain
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Santander, 39008, Spain
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Changhua, 500, Taiwan
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Kaohsiung City, 83301, Taiwan
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Taichung, 40447, Taiwan
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Tainan, 70403, Taiwan
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Tainan County, 71044, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 112, Taiwan
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Taoyuan, 333, Taiwan
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Bangkok, 10210, Thailand
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Bangkok, 10700, Thailand
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Chiang Mai, 50200, Thailand
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Dusit, 10300, Thailand
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Hat Yai, 90110, Thailand
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Muang, 40002, Thailand
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Ubonratchathani, 34000, Thailand
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Altındağ, 06230, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Erzurum, 25240, Turkey (Türkiye)
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Istanbul, 34180, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Cambridge, CB2 0QQ, United Kingdom
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Leeds, LS9 7TF, United Kingdom
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London, NW3 2QG, United Kingdom
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London, SE5 9RS, United Kingdom
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London, W12 0HS, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Hanoi, 100000, Vietnam
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Hanoi, 100000, Vietnam
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Ho Chi Minh City, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.

HEPATOCELLULAR CARCINOMA