Global trial tests new drugs to stop deadly liver cancer comeback

NCT ID NCT03847428

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This global study is testing whether two different drug combinations can prevent liver cancer from returning after patients have had successful surgery or ablation treatment. The trial involves 908 patients who are at high risk of their cancer coming back. Researchers are comparing the effectiveness of two immunotherapy-based treatments against a placebo to see which approach keeps patients cancer-free longer.

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Contacts and locations

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Locations

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Birmingham, Alabama, 35233, United States
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Mobile, Alabama, 36604, United States
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Phoenix, Arizona, 85054, United States
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Costa Mesa, California, 92627, United States
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La Jolla, California, 92093-0698, United States
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Long Beach, California, 90806, United States
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Orange, California, 92868, United States
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Sacramento, California, 95817, United States
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Washington D.C., District of Columbia, 20007, United States
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Miami, Florida, 33176, United States
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Tampa, Florida, 33606, United States
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Honolulu, Hawaii, 96819, United States
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Chicago, Illinois, 60637, United States
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Westwood, Kansas, 66205, United States
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Louisville, Kentucky, 40206, United States
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Shreveport, Louisiana, 71103, United States
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Detroit, Michigan, 48201, United States
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Grand Rapids, Michigan, 49503, United States
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Rochester, Minnesota, 55905, United States
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Omaha, Nebraska, 68198, United States
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New Brunswick, New Jersey, 08903, United States
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Albuquerque, New Mexico, 87109, United States
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New York, New York, 10021, United States
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Stony Brook, New York, 11794, United States
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Durham, North Carolina, 27710, United States
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Winston-Salem, North Carolina, 27157, United States
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Cleveland, Ohio, 44106, United States
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Philadelphia, Pennsylvania, 19104, United States
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Pittsburgh, Pennsylvania, 15212, United States
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Spartanburg, South Carolina, 29303, United States
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Knoxville, Tennessee, 37916, United States
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Memphis, Tennessee, 38104, United States
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Dallas, Texas, 75216, United States
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Madison, Wisconsin, 53715, United States
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Kogarah, 2217, Australia
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Melbourne, 3004, Australia
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Nedlands, 6009, Australia
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Westmead, 2145, Australia
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Innsbruck, 6020, Austria
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Linz, 4010, Austria
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Sankt Pölten, 3100, Austria
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Florianópolis, 88034-000, Brazil
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Porto Alegre, 90020-090, Brazil
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Porto Alegre, 90035-003, Brazil
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Rio de Janeiro, 20231-050, Brazil
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Santa Maria, 97015-450, Brazil
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Santo André, 09060-870, Brazil
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São José do Rio Preto, 15090-000, Brazil
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Vitória, 29043-272, Brazil
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Hamilton, Ontario, L8V 5C2, Canada
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Kingston, Ontario, K7L 2V7, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Québec, Quebec, G1R 2J6, Canada
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Beijing, 100021, China
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Beijing, 100142, China
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Beijing, 100730, China
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Bengbu, 233004, China
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Changchun, 130021, China
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Changsha, 410013, China
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Chengdu, 610041, China
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Fuzhou, 350005, China
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Guangzhou, 510000, China
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Guangzhou, 510080, China
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Guangzhou, 510515, China
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Hangzhou, 310003, China
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Hangzhou, 310016, China
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Hangzhou, 310022, China
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Harbin, 150049, China
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Hefei, 230001, China
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Hohhot, 010010, China
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Nanjing, 2100008, China
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Nanjing, 210002, China
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Ningbo, 315100, China
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Shanghai, 200032, China
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Shanghai, 201114, China
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Shanghai, 201318, China
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Tianjin, 300170, China
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Ürümqi, 830000, China
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Wuhan, 430079, China
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Xi'an, 710061, China
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Zhengzhou, 450052, China
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Alexandria, 21131, Egypt
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Asyut, 71511, Egypt
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Cairo, 11451, Egypt
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Cairo, 11588, Egypt
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Cairo, 11796, Egypt
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Dakahlia, 35516, Egypt
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New Cairo, 11566, Egypt
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Shebeen El Kom, 32511, Egypt
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Amiens, 88054, France
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Angers, 49933, France
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Besançon, 25000, France
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Clichy, 92110, France
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Dijon, 21079, France
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Nantes, 44093, France
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Nice, 06200, France
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Paris, 75571, France
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Pessac, 33604, France
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Toulouse, 31059, France
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Tours, 37049, France
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Berlin, 13353, Germany
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Bonn, 53105, Germany
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Chemnitz, 09116, Germany
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Cologne, 50937, Germany
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Freiburg im Breisgau, 79106, Germany
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Heidelberg, 69120, Germany
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Leipzig, 04103, Germany
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Lübeck, 23538, Germany
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München, 81377, Germany
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Tübingen, 72076, Germany
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Hong Kong, 0000, Hong Kong
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Hong Kong, 150001, Hong Kong
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Hong Kong, 999077, Hong Kong
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Hong Kong, Hong Kong
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Kwai Chung, 999077, Hong Kong
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Shatin, 00000, Hong Kong
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Bangalore, 560027, India
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Bangalore, 560092, India
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Hyderabad, 500032, India
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Kolkata, 700160, India
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Mumbai, 400012, India
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New Delhi, 110017, India
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New Delhi, 110076, India
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New Delhi, 110085, India
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Bologna, 40138, Italy
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Milan, 20132, Italy
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Milan, 20162, Italy
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Naples, 80131, Italy
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Roma, 00168, Italy
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Tricase, Lecce, 73039, Italy
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Verona, 37134, Italy
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Bunkyō City, 113-8655, Japan
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Fukuoka, 810-8563, Japan
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Gifu, 500-8513, Japan
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Hiroshima, 734-8551, Japan
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Kōtoku, 135-8550, Japan
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Kumamoto, 860-8556, Japan
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Kurume-shi, 830-0011, Japan
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Kyoto, 606-8507, Japan
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Kyoto, 612-8555, Japan
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Matsuyama, 790-8524, Japan
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Mitaka-shi, 181-8611, Japan
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Musashino-shi, 180-8610, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 466-8560, Japan
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Nagoya, 467-8602, Japan
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Osaka, 534-0021, Japan
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Osaka, 541-8567, Japan
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Osaka, 543-8555, Japan
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Osakasayama-shi, 589-8511, Japan
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Sapporo, 006-8555, Japan
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Sapporo, 060-0033, Japan
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Sendai, 980-0872, Japan
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Shinagawa-ku, 142-8666, Japan
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Shinjuku-ku, 160-0023, Japan
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Shinjuku-ku, 162-8655, Japan
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Shiwa-gun, 028-3695, Japan
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Takasaki-shi, 370-0829, Japan
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Tsu, 514-8507, Japan
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Wakayama, 641-8510, Japan
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Yokohama, 241-8515, Japan
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Yokohama, 245-8575, Japan
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Lima, LIMA 31, Peru
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Lima, LIMA 34, Peru
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Lima, LIMA 41, Peru
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San Isidro, 27, Peru
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City of Muntinlupa, 1780, Philippines
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Manila, 1000, Philippines
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Pasig, 1605, Philippines
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Bydgoszcz, 85-796, Poland
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Gdansk, 80-952, Poland
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Poznan, 61-866, Poland
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Warsaw, 02-034, Poland
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Ponce, 00716, Puerto Rico
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Barnaul, 656049, Russia
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Moscow, 119421, Russia
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Moscow, 125284, Russia
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Obninsk, 249031, Russia
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197044, Russia
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Saint Petersburg, 197758, Russia
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Yekaterinburg, 620905, Russia
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Singapore, 119074, Singapore
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Singapore, 308433, Singapore
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Singapore, 329563, Singapore
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Busan, 49241, South Korea
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Daegu, 41944, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Changhua, 500, Taiwan
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Tainan, 710, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 11217, Taiwan
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Taoyuan, 333, Taiwan
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Yunlin, 640, Taiwan
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Bangkok, 10210, Thailand
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Bangkok, 10300, Thailand
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Bangkok, 10330, Thailand
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Bangkok, 10700, Thailand
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Chiang Mai, 50200, Thailand
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Hat Yai, 90110, Thailand
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Khon Kaen, 40002, Thailand
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Pathum Thani, 12120, Thailand
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Ankara, 06100, Turkey (Türkiye)
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Ankara, 6200, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Malatya, 44100, Turkey (Türkiye)
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Hanoi, 100000, Vietnam
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Hanoi, 123, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Ho Chi Minh City, Vietnam
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Hochiminh, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

HEPATOCELLULAR CARCINOMA