New drug combo tested in major liver cancer trial

NCT ID NCT03298451

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study tested whether two immunotherapy drugs, durvalumab and tremelimumab, work better than the standard drug sorafenib for people with advanced liver cancer who haven't had other treatments. It involved over 1,300 patients worldwide. The main goal was to see if the new treatments help patients live longer.

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Contacts and locations

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Locations

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Los Angeles, California, 90048, United States
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Orange, California, 92868, United States
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San Francisco, California, 94158, United States
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Washington D.C., District of Columbia, 20007, United States
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Fort Myers, Florida, 33916, United States
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Jacksonville, Florida, 32224, United States
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Westwood, Kansas, 66205, United States
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Baltimore, Maryland, 21231, United States
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Ann Arbor, Michigan, 48109, United States
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Rochester, Minnesota, 55905, United States
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New York, New York, 10065, United States
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Charlotte, North Carolina, 28262, United States
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Portland, Oregon, 97213, United States
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Pittsburgh, Pennsylvania, 15237, United States
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Dallas, Texas, 74235, United States
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Dallas, Texas, 75216, United States
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Dallas, Texas, 75235, United States
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Houston, Texas, 77030, United States
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Houston, Texas, 77090, United States
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Murray, Utah, 84107, United States
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Barretos, Brazil
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Curitiba, Brazil
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Florianópolis, Brazil
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Porto Alegre, Brazil
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Rio de Janeiro, Brazil
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São Paulo, Brazil
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Calgary, Alberta, T2N 4N2, Canada
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Edmonton, Alberta, T6G 1Z2, Canada
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Hamilton, Ontario, L8V 5C2, Canada
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Kingston, Ontario, K7L 2V7, Canada
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London, Ontario, N6A 4L6, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Montreal, Quebec, H2X 0A9, Canada
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Québec, Quebec, G1R 2J6, Canada
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Sherbrooke, Quebec, J1H 5N4, Canada
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Beijing, China
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Changchun, China
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Changsha, China
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Chengdu, China
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Dalian, China
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Fuzhou, China
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Guangzhou, China
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Hangzhou, China
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Harbin, China
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Hefei, China
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Nanchang, China
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Nanjing, China
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Nanning, China
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Shanghai, China
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Suzhou, China
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Wuhan, China
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Xi'an, China
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Zhengzhou, China
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Clichy, France
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Lille, France
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Marseille, France
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Montpellier, France
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Nancy, France
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Nantes, France
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Nice, France
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Pessac, France
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Poitiers, France
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Reims, France
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Rouen, France
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Saint-Etienne, France
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Toulouse, France
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Villejuif, France
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Aachen, Germany
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Cologne, Germany
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Essen, Germany
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Hanover, Germany
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Heidelberg, Germany
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Leipzig, Germany
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Mainz, Germany
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München, Germany
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Tübingen, Germany
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Ulm, Germany
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Hong Kong, Hong Kong
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Bangalore, India
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Bhubneshwar, India
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Chennai, India
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Hubli, India
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Hyderabad, India
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Karmsad, India
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Mumbai, India
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Nashik, India
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New Delhi, India
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Benevento, Italy
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Meldola, Italy
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Milan, Italy
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Naples, Italy
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Perugia, Italy
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Pisa, Italy
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Roma, Italy
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Rozzano, Italy
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Bunkyoku, Japan
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Chiba, Japan
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Fukuoka, Japan
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Hiroshima, Japan
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Iizuka, Japan
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Kanazawa, Japan
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Kōtoku, Japan
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Kumamoto, Japan
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Kurume, Japan
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Matsuyama, Japan
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Mitakashi, Japan
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Musashino, Japan
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Nagoya, Japan
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Okayama, Japan
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Osaka, Japan
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Ōgaki, Japan
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Ōsaka-sayama, Japan
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Saga, Japan
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Sapporo, Japan
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Shiwa, Japan
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Suntogun, Japan
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Tsu, Japan
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Yokohama, Japan
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Moscow, Russia
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Murmansk, Russia
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Nizhny Novgorod, Russia
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Novosibirsk, Russia
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Obninsk, Russia
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Omsk, Russia
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Saint Petersburg, Russia
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Ufa, Russia
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Ilsan, Gyeonggi-do, 10408, South Korea
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Seongnam-si, Gyeonggi-do, 13620, South Korea
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Busan, 49241, South Korea
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Daegu, 41944, South Korea
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Seoul, 3080, South Korea
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Seoul, 3722, South Korea
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Seoul, 5505, South Korea
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Seoul, 6351, South Korea
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Barcelona, Spain
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Madrid, Spain
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Oviedo, Spain
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Pamplona Madrid, Spain
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Santander, Spain
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Chiayi City, Taiwan
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Kaohsiung City, Taiwan
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Taichung, Taiwan
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Tainan, Taiwan
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Taipei, Taiwan
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Taoyuan District, Taiwan
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Bangkok, Thailand
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Chang Mai, Thailand
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Khon Kaen, Thailand
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Phitsanulok, Thailand
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Songkhla, Thailand
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Dnipro, Ukraine
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IvanoFrankivsk, Ukraine
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Kharkiv, Ukraine
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Kropyvnitskyi, Ukraine
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Kyiv, Ukraine
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Lviv, Ukraine
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Odesa, Ukraine
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Uzhhorod, Ukraine
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Hanoi, Vietnam
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Hochiminh, Vietnam

Conditions

Explore the condition pages connected to this study.

HEPATOCELLULAR CARCINOMA