New drug duo shows promise against tough liver cancer

NCT ID NCT04487067

First seen Nov 01, 2025 · Last updated Apr 09, 2026 · Updated 22 times

Summary

This study tested a combination of two existing drugs (atezolizumab and bevacizumab) for people with advanced liver cancer that cannot be removed by surgery. The trial involved 152 patients who had not received any previous drug treatment for their cancer. Researchers wanted to see how safe and effective this drug combination would be in controlling the disease and extending survival.

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Contacts and locations

Locations

  • A.O. S. Orsola Malpighi

    Bologna, Emilia-Romagna, 40138, Italy

  • A.O. Universitaria S. Martino Di Genova

    Genoa, Liguria, 16132, Italy

  • A.O.U Careggi

    Florence, Tuscany, 50124, Italy

  • A.O.U. Cagliari-P.O. Monserrato

    Cagliari, Sardinia, 09100, Italy

  • A.O.U. Policlinico Paolo Giaccone

    Palermo, Sicily, 90127, Italy

  • Arcispedale Santa Maria Nuova

    Reggio Emilia, Emilia-Romagna, 42100, Italy

  • Azienda Osp Uni Seconda Università Degli Studi Di Napoli

    Naples, Campania, 80131, Italy

  • Azienda Ospedaliera Di Rilievo Nazionale E Di Alta Specializzazione Garibaldi

    Palermo, Sicily, 90127, Italy

  • Azienda Ospedaliera Ordine Mauriziano di Torino

    Turin, Piedmont, 10128, Italy

  • Azienda Ospedaliera San Camillo Forlanini

    Rome, Lazio, 00151, Italy

  • Azlenda Ospendaliero-Universitaria Pisana

    Pisa, Tuscany, 56100, Italy

  • Clinica Oncologica-Ospedali Riuniti Ancona

    Torrette, Tuscany, 60020, Italy

  • Fondazione IRCCS Ospedale Maggiore Policlinico

    Milan, Lombardy, 20122, Italy

  • Fondazione Pascale

    Naples, Campania, 80100, Italy

  • IOV - Istituto Oncologico Veneto - IRCCS

    Padova, Veneto, 35128, Italy

  • IRCCS Ospedale Casa Sollievo Della Sofferenza

    San Giovanni Rotondo, Apulia, 71013, Italy

  • Istituto Clinico Humanitas

    Rozzano, Lombardy, 20089, Italy

  • Istituto Nazionale Dei Tumori

    Milan, Lombardy, 20133, Italy

  • Ospedale del Mare

    Naples, Campania, 80147, Italy

  • Ospedali Riuniti - Bergamo

    Bergamo, Lombardy, 24128, Italy

  • Policlinico Universitario Agostino Gemelli

    Rome, Lazio, 00168, Italy

Conditions

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