Blood test may predict which lung cancer patients respond to immunotherapy

NCT ID NCT04790682

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing whether a liquid biopsy (a blood test that looks for tumor DNA) can predict how well immunotherapy works in people with advanced lung cancer. Researchers will track changes in ctDNA levels from before treatment to six weeks after, and see if those changes match tumor shrinkage on scans. The goal is to find a quick, non-invasive way to tell if the treatment is working, so patients can get the most effective care sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liquid biopsy (ctDNA testing)

What this could lead to

If successful, this could help doctors quickly identify which lung cancer patients will benefit from immunotherapy, avoiding ineffective treatments.

What could go wrong

This is an observational study, not a treatment trial. The test may not accurately predict responses, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung neoplasm metastatic malignant neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hopital Ambroise Pare

    RECRUITING

    Boulogne-Billancourt, 92100, France

    Contact

    Contact

  • Institut Curie

    RECRUITING

    Paris, 75005, France

    Contact

    Contact

  • Institut Curie

    RECRUITING

    Saint-Cloud, 92210, France

    Contact

    Contact