Liquid biopsy may unlock genetic secrets of brain AVMs

NCT ID NCT07103304

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study will analyze blood samples from the drainage vein of brain arteriovenous malformations (AVMs) in 16 adults undergoing embolization. The goal is to identify genetic mutations that may drive these abnormal vessels. Understanding these mutations could pave the way for future targeted drug treatments, but this research is purely observational and does not test any therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could point toward targeted drug therapies for brain arteriovenous malformations, potentially reducing the need for invasive procedures.

What could go wrong

This is a very small, early-stage observational study (16 participants) that only looks for genetic mutations. It does not test any treatment, so benefits are uncertain and far off.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

arteriovenous malformations of the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital la Pitié-Salpêtrière

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Caen

    Caen, 14033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Rouen

    Rouen, 76031, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••