Liquid biopsy may unlock genetic secrets of brain AVMs

NCT ID NCT07103304

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study will analyze blood samples from the drainage vein of brain arteriovenous malformations (AVMs) in 16 adults undergoing embolization. The goal is to identify genetic mutations that may drive these abnormal vessels. Understanding these mutations could pave the way for future targeted drug treatments, but this research is purely observational and does not test any therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could point toward targeted drug therapies for brain arteriovenous malformations, potentially reducing the need for invasive procedures.
What could go wrong
This is a very small, early-stage observational study (16 participants) that only looks for genetic mutations. It does not test any treatment, so benefits are uncertain and far off.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital la Pitié-Salpêtrière

    Paris, 75013, France

  • University Hospital of Caen

    Caen, 14033, France

  • University Hospital of Rouen

    Rouen, 76031, France

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