New combo therapy trial aims to control Tough-to-Treat cancer

NCT ID NCT05694871

Ongoing Disease control Sponsor: Alliance for Clinical Trials in Oncology Source: ClinicalTrials.gov ↗

Summary

This study is for adults with advanced dedifferentiated liposarcoma, a rare and aggressive cancer. It compares a standard cancer drug (palbociclib) alone versus the same drug combined with an immunotherapy drug (cemiplimab). The goal is to see if the two-drug combination is more effective at controlling the cancer and stopping it from getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States
Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122, United States
Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130, United States
Alegent Health Mercy Hospital

Council Bluffs, Iowa, 51503, United States
Atrium Health Pineville/LCI-Pineville

Charlotte, North Carolina, 28210, United States
BJC Outpatient Center at Sunset Hills

Sunset Hills, Missouri, 63127, United States
Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
CHI Health Good Samaritan

Kearney, Nebraska, 68847, United States
Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Centralia Oncology Clinic

Centralia, Illinois, 62801, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Commonwealth Cancer Center-Corbin

Corbin, Kentucky, 40701, United States
Creighton University Medical Center

Omaha, Nebraska, 68131, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Flaget Memorial Hospital

Bardstown, Kentucky, 40004, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Fresno Cancer Center

Fresno, California, 93720, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
HSHS Saint Elizabeth's Hospital

O'Fallon, Illinois, 62269, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Heartland Oncology and Hematology LLP

Council Bluffs, Iowa, 51503, United States
Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford Medical Center-Columbus

Novi, Michigan, 48377, United States
Henry Ford Medical Center-Fairlane

Dearborn, Michigan, 48126, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Hunterdon Medical Center

Flemington, New Jersey, 08822, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Illinois CancerCare - Washington

Washington, Illinois, 61571, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Dixon

Dixon, Illinois, 61021, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States
Jersey Shore Medical Center

Neptune City, New Jersey, 07753, United States
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Downtown Commons

Sacramento, California, 95814, United States
Kaiser Permanente Dublin

Dublin, California, 94568, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Medical Center-Vacaville

Vacaville, California, 95688, United States
Kaiser Permanente Moanalua Medical Center

Honolulu, Hawaii, 96819, United States
Kaiser Permanente Oakland-Broadway

Oakland, California, 94611, United States
Kaiser Permanente San Leandro

San Leandro, California, 94577, United States
Kaiser Permanente- Marshall Medical Offices

Redwood City, California, 94063, United States
Kaiser Permanente-Deer Valley Medical Center

Antioch, California, 94531, United States
Kaiser Permanente-Fremont

Fremont, California, 94538, United States
Kaiser Permanente-Fresno

Fresno, California, 93720, United States
Kaiser Permanente-Modesto

Modesto, California, 95356, United States
Kaiser Permanente-Oakland

Oakland, California, 94611, United States
Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, California, 95670, United States
Kaiser Permanente-Richmond

Richmond, California, 94801, United States
Kaiser Permanente-Roseville

Roseville, California, 95661, United States
Kaiser Permanente-San Francisco

San Francisco, California, 94115, United States
Kaiser Permanente-Santa Rosa

Santa Rosa, California, 95403, United States
Kaiser Permanente-Santa Teresa-San Jose

San Jose, California, 95119, United States
Kaiser Permanente-South San Francisco

South San Francisco, California, 94080, United States
Kaiser Permanente-Stockton

Stockton, California, 95210, United States
Kaiser Permanente-Vallejo

Vallejo, California, 94589, United States
Kaiser Permanente-Walnut Creek

Walnut Creek, California, 94596, United States
Kaiser San Rafael-Gallinas

San Rafael, California, 94903, United States
Littleton Adventist Hospital

Littleton, Colorado, 80122, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Marshfield Clinic - Wisconsin Rapids Center

Wisconsin Rapids, Wisconsin, 54494, United States
Marshfield Clinic-Chippewa Center

Chippewa Falls, Wisconsin, 54729, United States
Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States
Marshfield Clinic-Wausau Center

Wausau, Wisconsin, 54401, United States
Marshfield Medical Center - Ladysmith

Ladysmith, Wisconsin, 54848, United States
Marshfield Medical Center - Neillsville

Neillsville, Wisconsin, 54456, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mayo Clinic Hospital in Arizona

Phoenix, Arizona, 85054, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital of Carbondale

Carbondale, Illinois, 62902, United States
Memorial Medical Center

Springfield, Illinois, 62781, United States
Mercy Cancer Center

Merced, California, 95340, United States
Mercy Cancer Center - Carmichael

Carmichael, California, 95608, United States
Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758, United States
Mercy Cancer Center - Rocklin

Rocklin, California, 95765, United States
Mercy Cancer Center - Sacramento

Sacramento, California, 95816, United States
Mercy Medical Center

Durango, Colorado, 81301, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Mercyhealth Hospital and Cancer Center - Janesville

Janesville, Wisconsin, 53548, United States
Methodist Jennie Edmundson Hospital

Council Bluffs, Iowa, 51503, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Midlands Community Hospital

Papillion, Nebraska, 68046, United States
Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420, United States
Mission Hope Medical Oncology - Santa Maria

Santa Maria, California, 93444, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080, United States
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC

Omaha, Nebraska, 68114, United States
Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ

Council Bluffs, Iowa, 51503, United States
Nebraska Medicine-Bellevue

Bellevue, Nebraska, 68123, United States
Nebraska Medicine-Village Pointe

Omaha, Nebraska, 68118, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern Medicine Central DuPage Hospital

Winfield, Illinois, 60190, United States
Northwestern Medicine Glenview Outpatient Center

Glenview, Illinois, 60026, United States
Northwestern Medicine Grayslake Outpatient Center

Grayslake, Illinois, 60030, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern Medicine Orland Park

Orland Park, Illinois, 60462, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Associates PC

Omaha, Nebraska, 68114, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Pacific Central Coast Health Center-San Luis Obispo

San Luis Obispo, California, 93401, United States
Parker Adventist Hospital

Parker, Colorado, 80138, United States
Parkland Health Center - Farmington

Farmington, Missouri, 63640, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Porter Adventist Hospital

Denver, Colorado, 80210, United States
ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149, United States
ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066, United States
ProHealth Waukesha Memorial Hospital

Waukesha, Wisconsin, 53188, United States
Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rush - Copley Medical Center

Aurora, Illinois, 60504, United States
Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States
SIH Cancer Institute

Carterville, Illinois, 62918, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Elizabeth Regional Medical Center

Lincoln, Nebraska, 68510, United States
Saint Francis Cancer Center

Colorado Springs, Colorado, 80923, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Joseph Hospital

Lexington, Kentucky, 40504, United States
Saint Joseph Hospital East

Lexington, Kentucky, 40509, United States
Saint Joseph London

London, Kentucky, 40741, United States
Saint Joseph Mount Sterling

Mount Sterling, Kentucky, 40353, United States
Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
South Sacramento Cancer Center

Sacramento, California, 95823, United States
Southeast Cancer Center

Cape Girardeau, Missouri, 63703, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Southwest Oncology PC

Durango, Colorado, 81301, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
ThedaCare Cancer Care - Waupaca

Waupaca, Wisconsin, 54981, United States
ThedaCare Regional Cancer Center

Appleton, Wisconsin, 54911, United States
TriHealth Cancer Institute-Anderson

Cincinnati, Ohio, 45255, United States
TriHealth Cancer Institute-Westside

Cincinnati, Ohio, 45247, United States
UH Seidman Cancer Center at Firelands Regional Medical Center

Sandusky, Ohio, 44870, United States
UH Seidman Cancer Center at Saint John Medical Center

Westlake, Ohio, 44145, United States
UH Seidman Cancer Center at UH Avon Health Center

Avon, Ohio, 44011, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188, United States
University Hospitals Parma Medical Center

Parma, Ohio, 44129, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Virginia Cancer Institute

Richmond, Virginia, 23229, United States
Virginia Commonwealth University/Massey Cancer Center

Richmond, Virginia, 23298, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
West Virginia University Charleston Division

Charleston, West Virginia, 25304, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States
Woodland Memorial Hospital

Woodland, California, 95695, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED DEDIFFERENTIATED LIPOSARCOMA LOCALLY ADVANCED DEDIFFERENTIATED LIPOSARCOMA METASTATIC DEDIFFERENTIATED LIPOSARCOMA STAGE III SOFT TISSUE SARCOMA OF THE TRUNK AND EXTREMITIES AJCC V8 STAGE IV SOFT TISSUE SARCOMA OF THE TRUNK AND EXTREMITIES AJCC V8 UNRESECTABLE DEDIFFERENTIATED LIPOSARCOMA