Can a new drug head off multiple myeloma before it starts?

NCT ID NCT06140524

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests an investigational drug called linvoseltamab in people with two precancerous conditions—high-risk MGUS and non-high-risk smoldering multiple myeloma—that raise the risk of developing multiple myeloma. The goal is to see if the drug can eliminate abnormal plasma cells and reduce signs of disease. About 116 participants will receive the drug, and researchers will monitor side effects and how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Algemeen Ziekenhuis (AZ) Klina

    RECRUITING

    Brasschaat, Antwerpen, 2930, Belgium

  • Algemeen Ziekenhuis AZ Delta

    RECRUITING

    Roeselare, West-Vlaanderen, 8800, Belgium

  • Cork University Hospital

    RECRUITING

    Cork, T12 EC8P, Ireland

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Hospital Clinico Universitario Virgen De La Arrixaca

    RECRUITING

    El Palmar, Murcia, 30120, Spain

  • Hospital General Universitario Morales Meseguer

    RECRUITING

    Murcia, 30008, Spain

  • Hospital Sant Pau

    RECRUITING

    Barcelona, 08041, Spain

  • Hospital Universitari Mutua Terrassa

    RECRUITING

    Terrassa, Barcelona, 08221, Spain

  • Hospital Universitario Virgen de las Nieves

    RECRUITING

    Granada, Andalusia, 18014, Spain

  • Hospital de Cabuenes

    RECRUITING

    Gijón, Principality of Asturias, 33203, Spain

  • Istituto Romagnolo per lo Studio Dei Tumori Dino Amadori

    RECRUITING

    Meldola, Forli-Cesena, 47014, Italy

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Pratia MCM Krakow

    RECRUITING

    Krakow, Malopolska, 30-510, Poland

  • San Paolo Hospital

    RECRUITING

    Milan, Lombardy, 20142, Italy

  • Stony Brook University Hospital

    RECRUITING

    Stony Brook, New York, 11794, United States

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Universitaru Hospital La Princesa

    RECRUITING

    Madrid, 28006, Spain

  • University of Michigan Health

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Washington

    RECRUITING

    Seattle, Washington, 98109, United States

  • Wojewodzki Szpital Zespolony - Ludwik Rydygier Provincial Hospital

    RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

Conditions

Explore the condition pages connected to this study.