New hope for AL amyloidosis patients: experimental drug linvoseltamab enters trials

NCT ID NCT06292780

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 27 times

Summary

This study tests an experimental drug, linvoseltamab, in people with a rare disease called AL amyloidosis that has returned or not responded to other treatments. The goal is to find the right dose and see if the drug can reduce abnormal proteins causing organ damage. About 220 participants will be enrolled in two phases to check safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Clinica Universidad de Navarra - Pamplona

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Colorado Blood Cancer Institute/SCRI

    RECRUITING

    Denver, Colorado, 80218, United States

  • Hospital Universitari Son Espases

    RECRUITING

    Palma, Balearic Islands, 07120, Spain

  • Hospital de Cabuenes

    RECRUITING

    Gijón, Principality of Asturias, 33203, Spain

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • National and Kapodistrian University of Athens

    RECRUITING

    Athens, 11528, Greece

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Roswell Park Comprehensive Cancer Center

    RECRUITING

    Buffalo, New York, 14263, United States

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Seoul St. Mary's Hospital - The Catholic University of Korea

    RECRUITING

    Seoul, 065791, South Korea

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BQ, United Kingdom

  • University College London Hospitals

    RECRUITING

    London, NW1 2PG, United Kingdom

  • University Hospital La Fe

    RECRUITING

    Valencia, 46026, Spain

  • Universität de Barcelona- Institut d' Investigacions Biomediques August Pi i Sunyer (IDIBAPS)

    RECRUITING

    Barcelona, 08036, Spain

Conditions

Explore the condition pages connected to this study.