Can a Color-Enhanced scope catch what white light misses?
NCT ID NCT07745842
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial tests whether a special light mode called linked color imaging (LCI) helps doctors find more sessile serrated lesions (a type of precancerous colon polyp) during colonoscopy than standard white light. About 2,000 adults aged 45 and older having their first screening colonoscopy will be randomly assigned to have the procedure done in two passes, with the order of light modes switched. The goal is to see if LCI reduces the number of lesions missed on the first look.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- linked color imaging (LCI) during colonoscopy
- What this could lead to
- If LCI proves better at spotting these lesions, it could lead to more accurate colonoscopies and potentially lower colorectal cancer risk.
- What could go wrong
- The benefit may be small or not consistent across different doctors and centers. Also, the trial is not yet complete, so results are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.