New hope for constipated babies? drug trial shows promise

NCT ID NCT05760313

First seen Jan 10, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study tested a drug called linaclotide in 19 children aged 6 months to under 2 years with functional constipation (hard, infrequent stools). The goal was to see if it safely improves bowel movements and reduces straining. Children took a liquid form of the drug daily for 4 weeks, and parents tracked symptoms. The study is complete, but results are not yet public.

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Contacts and locations

Locations

  • Acibadem City Clinic Tokuda University Hospital EAD /ID# 251232

    Sofia, 1407, Bulgaria

  • Advanced Research Center /ID# 248763

    Anaheim, California, 92805, United States

  • ClinPoint Trials /ID# 251534

    Waxahachie, Texas, 75165-1430, United States

  • Coastal Pediatric Research - Summerville /ID# 253534

    Summerville, South Carolina, 29486, United States

  • Coastal Pediatric Research - West Ashley B /ID# 248693

    Charleston, South Carolina, 29414, United States

  • Debreceni Egyetem-Klinikai Kozpont /ID# 250793

    Debrecen, Hajdú-Bihar, 4032, Hungary

  • Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 252298

    London, Greater London, E1 2ES, United Kingdom

  • Frederick County Pediatrics /ID# 251555

    New Market, Maryland, 21774-6154, United States

  • Great Ormond Street Children's Hospital /ID# 253333

    London, Greater London, WC1N 3HZ, United Kingdom

  • HELIOS Klinikum Wuppertal /ID# 249022

    Wuppertal, 42283, Germany

  • HealthStar Research of Hot Springs PLLC /ID# 251553

    Hot Springs, Arkansas, 71913, United States

  • Houston Clinical Research Associates /ID# 261571

    Houston, Texas, 77090-2633, United States

  • Institut za zdravstvenu zastitu majke i deteta Srbije Dr Vukan Cupic /ID# 252485

    Belgrade, Beograd, 11000, Serbia

  • Institute for Child and Youth Health Care of Vojvodina /ID# 252482

    Novi Sad, 21000, Serbia

  • Kinderarztpraxis Dr. Froehlich /ID# 252050

    Forchheim, 91301, Germany

  • Kindred Medical Institute - Corona /ID# 251535

    Corona, California, 92879-3104, United States

  • Klinicki bolnicki centar Osijek /ID# 252795

    Osijek, County of Osijek-Baranja, 31000, Croatia

  • Klinicki bolnicki centar Sestre milosrdnice /ID# 252798

    Zagreb, City of Zagreb, 10000, Croatia

  • Klinicki bolnicki centar Zagreb /ID# 252796

    Zagreb, City of Zagreb, 10000, Croatia

  • Klinika za dječje bolesti Zagreb /ID# 252792

    Zagreb, City of Zagreb, 10000, Croatia

  • Michigan Center of Medical Research /ID# 253536

    Farmington Hills, Michigan, 48334, United States

  • Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 252299

    Norwich, Norfolk, NR4 7UY, United Kingdom

  • Nova Clinic /ID# 249023

    Varna, 9000, Bulgaria

  • Prime Clinical Research - Mansfield - East Broad Street /ID# 262947

    Mansfield, Texas, 76063, United States

  • Prohealth Research Center /ID# 248696

    Doral, Florida, 33166, United States

  • Russells Hall Hospital /ID# 252660

    Dudley, DY1 2HQ, United Kingdom

  • South Miami Medical & Research Group Inc. /ID# 248765

    Miami, Florida, 33155, United States

  • Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 251229

    Sofia, 1606, Bulgaria

  • UMHAT Kanev /ID# 248931

    Rousse, 7002, Bulgaria

  • UMHAT Sveti Georgi /ID# 250808

    Plovdiv, 4002, Bulgaria

  • Universitaetsklinikum Muenster /ID# 251965

    Münster, North Rhine-Westphalia, 48149, Germany

  • University Children's Hospital 'Tirsova' /ID# 252483

    Belgrade, Beograd, 11000, Serbia

  • Valencia Medical & Research Center /ID# 251533

    Miami, Florida, 33165, United States

  • Velocity Clinical Research - Lafayette /ID# 263873

    Lafayette, Louisiana, 70508, United States

  • Velocity Clinical Research - Phoenix /ID# 263871

    Phoenix, Arizona, 85006, United States

  • Velocity Clinical Research Macon /ID# 263959

    Macon, Georgia, 31210-6583, United States

  • Velocity Clinical Research Washington DC /ID# 263872

    Washington D.C., District of Columbia, 20016-4300, United States

  • Velocity Clinical Research- Hastings Nebraska /ID# 260932

    Hastings, Nebraska, 68901-2640, United States

Conditions

Explore the condition pages connected to this study.