Spray before the needle: can lidocaine ease IV pain?
NCT ID NCT06354816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a 10% lidocaine spray, applied to the skin two minutes before inserting an IV catheter, reduces pain in women aged 18-45. Each volunteer received four IV insertions—two on the hand and two on the forearm—with either the spray or a placebo. The goal was to see if the spray made the procedure less painful using a standard pain scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lidocaine 10% spray
What this could lead to
If it works, this could offer a simple, quick way to reduce pain during IV insertion for many patients.
What could go wrong
This is a small, early-phase trial with only 40 women, so results may not apply to everyone. The pain relief might be minimal or not better than placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ordensklinikum Linz GmbH
Linz, Upper Austria, 4010, Austria