Spray before the needle: can lidocaine ease IV pain?

NCT ID NCT06354816

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a 10% lidocaine spray, applied to the skin two minutes before inserting an IV catheter, reduces pain in women aged 18-45. Each volunteer received four IV insertions—two on the hand and two on the forearm—with either the spray or a placebo. The goal was to see if the spray made the procedure less painful using a standard pain scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Lidocaine 10% spray
What this could lead to
If it works, this could offer a simple, quick way to reduce pain during IV insertion for many patients.
What could go wrong
This is a small, early-phase trial with only 40 women, so results may not apply to everyone. The pain relief might be minimal or not better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ordensklinikum Linz GmbH

    Linz, Upper Austria, 4010, Austria

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