New hope for newborn seizures: levetiracetam tested as safer alternative

NCT ID NCT07401433

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested whether levetiracetam works better and safer than the standard drug phenobarbitone for stopping seizures in newborns. 260 babies with seizures received either levetiracetam or phenobarbitone. Researchers measured how quickly seizures stopped and if they returned. The goal is to find a treatment that controls seizures faster with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
levetiracetam
What this could lead to
If successful, levetiracetam could become a safer, more effective first-line treatment for neonatal seizures, reducing brain injury risk.
What could go wrong
This is a single-center completed trial; results may not apply broadly. Levetiracetam may not outperform phenobarbitone in all settings, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gomal Medical College

    Dera Ismāīl Khān, KPK, 29111, Pakistan

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