Can a tiny dose of an epilepsy drug slow Alzheimer's before symptoms start?

NCT ID NCT07477431

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study tests whether a very low dose of levetiracetam, a drug used for epilepsy, can reduce abnormal overactivity in a key memory area of the brain. It includes 40 people who have a parent or sibling with Alzheimer's and have memory concerns but still score normally on thinking tests. Participants will take the drug or a placebo for 4 weeks each, without knowing the order, and undergo brain scans and memory tasks to see if the drug helps normalize brain signals.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

  • Toronto Western Hospital

    RECRUITING

    Toronto, Ontario, M5T 2S8, Canada

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