Intensive combo therapy tested in High-Risk leukemia

NCT ID NCT00792948

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study tested a multi-part treatment for adults with a specific, aggressive type of acute lymphoblastic leukemia (ALL). The goal was to see if combining intensive chemotherapy, a targeted drug called dasatinib, and for some patients, a stem cell transplant from a donor, could effectively control the cancer and prevent it from returning. Researchers measured how long patients stayed cancer-free after treatment and monitored side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMG Libertyville - Oncology

Libertyville, Illinois, 60048, United States
AdventHealth Orlando

Orlando, Florida, 32803, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Avera McKennan Hospital and University Health Center

Sioux Falls, South Dakota, 57117-5045, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Baylor University Medical Center

Dallas, Texas, 75246, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Bronson Battle Creek

Battle Creek, Michigan, 49017, United States
Cancer Care Center at Island Hospital

Anacortes, Washington, 98221, United States
Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States
Cancer Center of Kansas - McPherson

McPherson, Kansas, 67460, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Liberal

Liberal, Kansas, 67905, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Research Consortium of West Michigan NCORP

Grand Rapids, Michigan, 49503, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center

Wilmington, Ohio, 45177, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Dayton NCI Community Oncology Research Program

Dayton, Ohio, 45459, United States
DuPage Medical Group-Ogden

Naperville, Illinois, 60563, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Evergreen Hematology and Oncology PS

Spokane, Washington, 99218, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview

Fort Wayne, Indiana, 46845, United States
Franciscan Saint Francis Health-Beech Grove

Beech Grove, Indiana, 46107, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Glacier Oncology PLLC

Kalispell, Montana, 59901, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Grandview Hospital

Dayton, Ohio, 45405, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greene Memorial Hospital

Xenia, Ohio, 45385, United States
Harborview Medical Center

Seattle, Washington, 98104, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States
HaysMed

Hays, Kansas, 67601, United States
Hematology Oncology Associates of Illinois - Skokie

Skokie, Illinois, 60076, United States
Hematology Oncology Associates of Illinois-Highland Park

Highland Park, Illinois, 60035, United States
Hematology and Oncology Associates

Chicago, Illinois, 60611, United States
Hematology/Oncology Clinic PLLC

Baton Rouge, Louisiana, 70809, United States
Highline Medical Center-Main Campus

Burien, Washington, 98166, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Hutchinson Regional Medical Center

Hutchinson, Kansas, 67502, United States
Illinois Cancer Specialists-Niles

Niles, Illinois, 60714, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
LSU Health Sciences Center at Shreveport

Shreveport, Louisiana, 71103, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MacNeal Hospital and Cancer Center

Berwyn, Illinois, 60402, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Mercy Hospital Pittsburg

Pittsburg, Kansas, 66762, United States
Mercy Medical Center-Sioux City

Sioux City, Iowa, 51102, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Minor and James Medical PLLC

Seattle, Washington, 98104, United States
Montana Cancer Consortium NCORP

Billings, Montana, 59102, United States
Montana Cancer Specialists

Missoula, Montana, 59802, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Montefiore Medical Center-Weiler Hospital

The Bronx, New York, 10461, United States
Mount Nittany Medical Center

State College, Pennsylvania, 16803, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
Northwestern University

Chicago, Illinois, 60611, United States
PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States
PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Presence Saint Mary's Hospital

Kankakee, Illinois, 60901, United States
Reid Health

Richmond, Indiana, 47374, United States
Rocky Mountain Oncology

Casper, Wyoming, 82609, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
SSM Health Saint Louis University Hospital

St Louis, Missouri, 63104, United States
Saint George Regional Medical Center

St. George, Utah, 84770, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Rita's Medical Center

Lima, Ohio, 45801, United States
Saint Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Salina Regional Health Center

Salina, Kansas, 67401, United States
Sandra L Maxwell Cancer Center

Cedar City, Utah, 84720, United States
Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States
Skagit Valley Hospital

Mount Vernon, Washington, 98274, United States
Southwest Medical Center

Liberal, Kansas, 67901, United States
Spectrum Health Big Rapids Hospital

Big Rapids, Michigan, 49307, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026, United States
Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The Jewish Hospital

Cincinnati, Ohio, 45236, United States
The University of Kansas Cancer Center-South

Kansas City, Missouri, 64131, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112, United States
UF Health Cancer Institute - Gainesville

Gainesville, Florida, 32610, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
University Health Truman Medical Center

Kansas City, Missouri, 64108, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center - Lee's Summit

Lee's Summit, Missouri, 64064, United States
University of Kansas Cancer Center - North

Kansas City, Missouri, 64154, United States
University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210, United States
University of Kansas Cancer Center-West

Kansas City, Kansas, 66112, United States
University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Wenatchee Valley Hospital and Clinics

Wenatchee, Washington, 98801, United States
Wesley Medical Center

Wichita, Kansas, 67214, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States

Conditions

Explore the condition pages connected to this study.

ACUTE LYMPHOBLASTIC LEUKEMIA ADULT B ACUTE LYMPHOBLASTIC LEUKEMIA ADULT B ACUTE LYMPHOBLASTIC LEUKEMIA WITH T(9;22)(Q34.1;Q11.2); BCR-ABL1 ADULT L1 ACUTE LYMPHOBLASTIC LEUKEMIA ADULT L2 ACUTE LYMPHOBLASTIC LEUKEMIA ADULT T ACUTE LYMPHOBLASTIC LEUKEMIA RECURRENT ADULT ACUTE LYMPHOBLASTIC LEUKEMIA