Scientists test Immune-Boosting combo against tough blood cancers
NCT ID NCT02890329
Summary
This early-stage study is testing the safety and best dose of a two-drug combination for patients with advanced myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that has returned or not responded to prior treatment. The trial combines a chemotherapy drug (decitabine) with an immunotherapy drug (ipilimumab) that aims to help the body's own immune system fight the cancer. It is enrolling up to 54 adults whose cancer has progressed despite previous therapies, including some who have had a stem cell transplant.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
Conditions
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