Could a breast cancer drug treat ectopic pregnancy?

NCT ID NCT07624903

Not yet recruiting Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether letrozole, a drug that lowers estrogen, can treat early ectopic pregnancy as effectively as the standard drug methotrexate. The trial will enroll 70 women with confirmed ectopic pregnancy and low hormone levels. Participants will receive one of the two drugs, and success will be measured by how well the pregnancy resolves.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Letrozole (a drug that blocks estrogen production) and methotrexate (a drug that stops cell growth)
What this could lead to: If letrozole works as well as methotrexate, it could offer a simpler, less toxic treatment option for early ectopic pregnancy, avoiding surgery.
What could go wrong: This is a small, early-phase trial with only 70 participants. It may not show a clear benefit, and letrozole's safety for this use is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ectopic pregnancy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ECTOPIC PREGNANCY

Contacts and locations

Locations

Kafr El-Sheikh University

Kafr ash Shaykh, Kafr el-Sheikh Governorate, 33511, Egypt

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