Could a common fertility drug improve miscarriage care?
NCT ID NCT07160855
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether taking letrozole before misoprostol helps women with missed miscarriage pass pregnancy tissue more completely than misoprostol alone. Ninety-two women in early pregnancy (up to 13 weeks) will be randomly assigned to receive either letrozole or a placebo for three days, followed by misoprostol. The main goal is to see if the combination leads to a complete abortion within 24 hours without needing surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
letrozole and misoprostol
What this could lead to
If it works, this could offer a more effective medication option for managing missed miscarriage, reducing the need for surgical procedures.
What could go wrong
This is a small, early-phase trial with only 92 participants. Adding letrozole may not improve outcomes and could cause additional side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MISCARRIAGE IN FIRST TRIMESTER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Nishtar Medical University and Hospital
RECRUITINGMultan, Punjab Province, 60000, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••