New hope for chronic hives sufferers: experimental drug lesigercept in human trials

NCT ID NCT07415551

First seen Feb 19, 2026 · Last updated May 14, 2026 · Updated 9 times

Summary

This study tests a new drug called lesigercept for people with chronic spontaneous urticaria (long-term hives) that antihistamines don't fully control. About 150 adults will receive either the drug or a placebo for 12 weeks to see if it reduces itching and welts. The goal is to find a better treatment option for those whose hives persist despite standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ALL-MED Specjalistyczna Opieka Medyczna

    NOT_YET_RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 53-201, Poland

  • Ajou University Hospital

    NOT_YET_RECRUITING

    Gyeonggi-do, Suwon, 16499, South Korea

  • Alergo-Med Ośrodek Badań Klinicznych Sp. z o.o.

    NOT_YET_RECRUITING

    Tarnów, Lesser Poland Voivodeship, 33-100, Poland

  • Alergologia Plus Sp. z o. o.

    NOT_YET_RECRUITING

    Poznan, Greater Poland Voivodeship, 60-693, Poland

  • Asan Medical Center

    NOT_YET_RECRUITING

    Seoul, Songpa-gu, 05505, South Korea

  • Bio Zdrowie sp. z o.o.

    NOT_YET_RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-698, Poland

  • Centrum Medyczne ALL-MED

    NOT_YET_RECRUITING

    Krakow, Lesser Poland Voivodeship, 30-033, Poland

  • Centrum Nowoczesnych Terapii "Dobry Lekarz" Sp. z o.o.

    NOT_YET_RECRUITING

    Krakow, Lesser Poland Voivodeship, 31-011, Poland

  • Chung-Ang University Hospital

    RECRUITING

    Seoul, Dongjak-gu, 06973, South Korea

  • Clinic Infertility Treatment Angelius Provita (Centrum Medyczne Angelius Provita)

    NOT_YET_RECRUITING

    Katowice, Silesian Voivodeship, 40-611, Poland

  • DERMACEUM sp. z o.o., DERMACEUM Centrum Medyczne

    NOT_YET_RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 53-613, Poland

  • Dermatology Hospital of Southern Medical University (Guangdong Province Dermatology Hospital)

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510000, China

  • Diagnostic & Consultative Centre Ascendent EOOD

    NOT_YET_RECRUITING

    Sofia, Sofia, 1202, Bulgaria

  • Hallym University Kangnam Sacred Heart Hospital

    NOT_YET_RECRUITING

    Seoul, Seoul, 07441, South Korea

  • Inha University Hospital

    NOT_YET_RECRUITING

    Incheon, Incheon, 22332, South Korea

  • Keimyung University Dongsan Hospital

    RECRUITING

    Daegu, Dalseo-gu, 42601, South Korea

  • Korea University Ansan Hospital

    NOT_YET_RECRUITING

    Gyeonggi-do, Danwon-gu, 15355, South Korea

  • Kyung Hee University Hospital at Gangdong

    NOT_YET_RECRUITING

    Seoul, Seoul, 05278, South Korea

  • Medical Center Hera EOOD

    NOT_YET_RECRUITING

    Sofia, Sofia, 1510, Bulgaria

  • NZOZ GynCentrum Oddział Libero

    NOT_YET_RECRUITING

    Katowice, Silesian Voivodeship, 40-600, Poland

  • Prof. Dorota Krasowska LUXDERM Specjalistyczny Gabinet Dermatologiczny

    NOT_YET_RECRUITING

    Lublin, Lublin Voivodeship, 20-573, Poland

  • Prywatny Gabinet Internistyczno-Alergologiczny Prof. dr hab. Zenon Siergiejko

    NOT_YET_RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-010, Poland

  • Pusan National University Yangsan Hospital

    NOT_YET_RECRUITING

    Yangsan, Gyeongsangnam-do, 50612, South Korea

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Gyeonggi-do, Bundang-gu, 13620, South Korea

  • Seoul St. Mary's Hospital, The Catholic University of Korea

    RECRUITING

    Seoul, Seocho-gu, 06591, South Korea

  • Severance Hospital, Yonsei University Health System

    NOT_YET_RECRUITING

    Seoul, Seodaemun-gu, 03722, South Korea

  • The University of Hong Kong-Shenzhen Hospital

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518053, China

  • UMHAT "Aleksandrovska"

    NOT_YET_RECRUITING

    Sofia, Sofia, 1431, Bulgaria

  • UMHATEM "N. I. Pirogov"

    NOT_YET_RECRUITING

    Sofia, Sofia, 1606, Bulgaria

  • Uniwersytecki Szpital Kliniczny w Opolu

    NOT_YET_RECRUITING

    Opole, Opolskie Voivodeship, 45-401, Poland

Conditions

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