New hope for Tough-to-Treat breast cancer: Triple-Drug combo trial opens

NCT ID NCT05286437

First seen Jan 08, 2026 · Last updated May 07, 2026 · Updated 19 times

Summary

This study tests a combination of three drugs—lenvatinib, pembrolizumab, and letrozole—in people with advanced hormone receptor-positive, HER2-negative breast cancer that has stopped responding to standard hormone therapy. The goal is to see if this mix can shrink tumors or slow the disease. About 40 adults whose cancer has spread or cannot be removed will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, 169610, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.