New combo therapy targets genetic weakness in advanced cancers
NCT ID NCT07417501
First seen Feb 22, 2026 · Last updated May 15, 2026 · Updated 15 times
Summary
This study tests whether combining lenvatinib (a daily pill) with a PD-1 inhibitor (an immunotherapy given by IV every 3 weeks) can shrink or stop advanced solid tumors that have a specific genetic change called 11q13 amplification. About 60 adults with various cancers (like esophageal, head and neck, breast, lung, or liver) that have this genetic marker will receive the same treatment. Researchers will track tumor response using scans and monitor side effects to see if this combination is effective and safe.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tongji Hospital
Wuhan, Hubei, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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