New hope for kidney cancer: which drug combo works best after immunotherapy fails?
NCT ID NCT05012371
First seen Nov 01, 2025 · Last updated Jun 09, 2026 · Updated 38 times
Summary
This study tests two treatment options for people with advanced kidney cancer that has spread and continued to grow after immunotherapy. One group gets a combination of two drugs (lenvatinib and everolimus), while the other gets a single drug (cabozantinib). The goal is to see which approach better slows cancer growth and improves quality of life. About 90 adults with clear cell kidney cancer who have had 1-2 prior treatments are taking part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
Conditions
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