New drug shows promise for CVID immune chaos in early trial
NCT ID NCT06897358
First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 27 times
Summary
This study tests a drug called leniolisib in 20 people with common variable immunodeficiency (CVID), a condition that weakens the immune system. All participants will receive the drug for 6 months, starting at a low dose and increasing. The main goal is to check if the drug is safe and tolerable, and to see if it helps control immune system problems like swollen lymph nodes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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IIS La Fe
Valencia, Spain
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Lahey Hospital & Medical Center
Burlington, Massachusetts, 01805, United States
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Leeds Teaching Hospital NHS Trust
Leeds, United Kingdom
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Mount Sinai Hospital
New York, New York, 10029, United States
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National Institute of Health
Bethesda, Maryland, 20892, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.