Old drug, new hope: lenalidomide takes on rare histiocyte disorders

NCT ID NCT02523040

First seen Jan 04, 2026 · Last updated May 20, 2026 · Updated 22 times

Summary

This study tests whether the chemotherapy drug lenalidomide can shrink or stop rare immune cell diseases called Langerhans cell histiocytosis, Erdheim-Chester disease, and histiocytic sarcoma. Twelve adults with active disease that needs treatment will receive lenalidomide and be monitored for response. The goal is to see how many people achieve disease control, not a permanent cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LANGERHANS CELL HISTIOCYTOSIS (LCH) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.