New combo therapy shows promise for myeloma relapse after transplant

NCT ID NCT03413800

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a two-step treatment for people whose multiple myeloma returned after a donor stem cell transplant. First, patients received lenalidomide and dexamethasone to reduce cancer and prepare the immune system. Then, they received donor immune cells (lymphocyte infusions) to boost the body's ability to fight the cancer. The goal was to improve disease control and delay progression, while monitoring side effects like graft-versus-host disease. Ten adults aged 18-65 participated.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CIUSSS de l'Est-de-l'île-de-Montréal, Installation Hôpital Maisonneuve Rosemond

    Montreal, Quebec, H1T2M4, Canada