Leg supplement shows promise for heavy, tired legs
NCT ID NCT07185386
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a dietary supplement containing diosmin, hesperidin, bromelain, and ruscus aculeatus in 80 adults with early signs of chronic venous disease, like heavy or swollen legs. Participants took the supplement for 12 weeks, and researchers measured changes in quality of life using a standard questionnaire. The goal was to see if the supplement could ease symptoms and improve daily comfort.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AOU Policlinico Sant'Orsola Malpighi
Bologna, BO, 40138, Italy
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IRCCS San Raffaele Pisana
Roma, Roma, 00163, Italy
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Università degli Studi Magna Graecia
Catanzaro, CZ, 88100, Italy
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Vi.Gi. Centro Polispecialistico
Vibo Valentia, VV, 89900, Italy
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