New pacing technique aims to cut heart failure risk
NCT ID NCT05015660
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a newer pacing method called left bundle branch pacing (LBBP) with standard right ventricular pacing in 1,300 people who need a pacemaker for heart block. Standard pacing can sometimes weaken the heart over time, leading to heart failure. LBBP tries to mimic the heart's natural electrical system to avoid that. The trial will track heart failure events, heart function, and survival over several years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Left bundle branch pacing lead (device) vs right ventricular active fixation lead (device)
- What this could lead to
- If successful, this could show that left bundle pacing lowers the risk of heart failure and death compared to standard pacing, offering a better pacing option for patients with heart block.
- What could go wrong
- This is a large but still ongoing trial, and results may not show a clear benefit. The procedure is newer and may have unknown risks or be less effective in some patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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McGill University Health Centre-Research Institute
RECRUITINGMontreal, Quebec, H3Y2T6, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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