New Alzheimer's drug shows promise in slowing memory loss

NCT ID NCT01767311

Completed Disease control Sponsor: Eisai Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether an investigational drug called lecanemab (BAN2401) could slow the progression of early Alzheimer's disease. It involved 856 people with either mild cognitive impairment or mild dementia due to Alzheimer's. Participants received different doses of the drug or a placebo via IV infusion for 18 months, followed by an optional long-term extension phase, to see if it improved memory and thinking skills and reduced amyloid plaques in the brain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Eisai Trial Site #1

Otake-shi, Hiroshima, Japan
Eisai Trial Site #1

Himeji-shi, Hyōgo, Japan
Eisai Trial Site #1

Kobe, Hyōgo, Japan
Eisai Trial Site #1

Nishinomiya-shi, Hyōgo, Japan
Eisai Trial Site #1

Kyoto, Kyoto, Japan
Eisai Trial Site #1

Kurashiki-shi, Okayama-ken, Japan
Eisai Trial Site #1

Osaka, Osaka, Japan
Eisai Trial Site #1

Saitama-shi, Saitama, Japan
Eisai Trial Site #1

Itabashi-ku, Tokyo-To, Japan
Eisai Trial Site #1

Shinjuku-ku, Tokyo-To, Japan
Eisai Trial Site #2

Himeji-shi, Hyōgo, Japan
Eisai Trial Site #2

Shinjuku-ku, Tokyo-To, Japan
Eisai Trial Site #3

Himeji-shi, Hyōgo, Japan
Facility #1

Birmingham, Alabama, 35294, United States
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Phoenix, Arizona, 85004, United States
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Tucson, Arizona, 85724, United States
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Carson, California, 90746, United States
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Lomita, California, 90717, United States
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Long Beach, California, 90806, United States
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Los Alamitos, California, 90720, United States
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Los Angeles, California, 90024, United States
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Orange, California, United States
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Oxnard, California, 93030, United States
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San Diego, California, 92123, United States
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Denver, Colorado, 80239-3133, United States
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New Haven, Connecticut, 06510, United States
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Atlantis, Florida, 33462, United States
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Boca Raton, Florida, 33431, United States
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Bradenton, Florida, 34205, United States
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Deerfield Beach, Florida, 33064, United States
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Delray Beach, Florida, 33445, United States
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Fort Myers, Florida, 33912, United States
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Hallandale, Florida, 33009, United States
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Hialeah, Florida, 33016, United States
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Lake Worth, Florida, 33449, United States
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Leesburg, Florida, 34748, United States
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Miami, Florida, 33133, United States
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Miami Springs, Florida, 33166, United States
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Naples, Florida, 34102, United States
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Ocala, Florida, 34471, United States
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Orlando, Florida, 32806, United States
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Palm Beach Gardens, Florida, 33410, United States
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St. Petersburg, Florida, 33713, United States
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Sunrise, Florida, 33351, United States
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Tampa, Florida, 33613, United States
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The Villages, Florida, United States
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Atlanta, Georgia, 30329, United States
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Columbus, Georgia, 31909, United States
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Decatur, Georgia, 30033, United States
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Chicago, Illinois, 60640, United States
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Elk Grove Village, Illinois, 60007, United States
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Elkhart, Indiana, 46514, United States
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Indianapolis, Indiana, 46202, United States
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Wichita, Kansas, 67214, United States
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Lexington, Kentucky, 40504, United States
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Boston, Massachusetts, 02115, United States
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Burlington, Massachusetts, 01805, United States
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Newton, Massachusetts, 02459, United States
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Ann Arbor, Michigan, 48105-2945, United States
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East Lansing, Michigan, United States
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Farmington Hills, Michigan, 48334, United States
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Lansing, Michigan, 48824, United States
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West Bloomfield, Michigan, 48322, United States
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St Louis, Missouri, 63118, United States
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Eatontown, New Jersey, 07724, United States
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Toms River, New Jersey, 08755, United States
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Albany, New York, 12206, United States
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Amherst, New York, 14226, United States
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Latham, New York, 12110, United States
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New York, New York, 10016, United States
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Rochester, New York, 14620, United States
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Charlotte, North Carolina, 28211, United States
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Centerville, Ohio, 45459, United States
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Oklahoma City, Oklahoma, 73112, United States
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Portland, Oregon, 97239, United States
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Abington, Pennsylvania, 19001, United States
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Jenkintown, Pennsylvania, 19046, United States
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East Providence, Rhode Island, 02914, United States
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Knoxville, Tennessee, 37920, United States
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Austin, Texas, 78757, United States
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Dallas, Texas, 75214, United States
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Houston, Texas, 77074, United States
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San Antonio, Texas, 78229, United States
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Bennington, Vermont, 05201, United States
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Richmond, Virginia, 23294, United States
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Milwaukee, Wisconsin, 53226, United States
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Kentville, Nova Scotia, Canada
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Kingston, Ontario, Canada
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Ottawa, Ontario, Canada
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Peterborough, Ontario, Canada
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Toronto, Ontario, Canada
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Greenfield Park, Quebec, Canada
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Montreal, Quebec, Canada
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Verdun, Quebec, Canada
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Québec, Canada
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Strasbourg, Bas Rhin, France
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Toulouse, Haute Garonne, France
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Paris, Paris, France
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Bron, France
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Paris, France
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Rennes, France
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Villeurbanne, France
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Gunzburg, Baden-Wurttemberg, Germany
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Karlstadt am Main, Bavaria, Germany
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Hanover, Lower Saxony, Germany
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Mittweida, Saxony, Germany
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Hoppegarten, State of Berlin, Germany
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Berlin, Germany
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Günzburg, Germany
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Hamburg, Germany
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Heidelberg, Germany
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Leipzig, Germany
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Mannheim, Germany
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München, Germany
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Tübingen, Germany
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Brescia, Italy
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Genova, Italy
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Milan, Italy
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Parma, Italy
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Perugia, Italy
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Pisa, Italy
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Roma, Italy
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Amsterdam, Netherlands
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Seongnam-si, Gyeonggi-do, South Korea
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Pusan, Gyeongsangnam-do, South Korea
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Sant Cugat Del Vallés, Barcelona, Spain
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Donostia / San Sebastian, Guipuzcoa, Spain
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Barakaldo, Vizcaya, Spain
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Alicante, Spain
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Barcelona, Spain
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Madrid, Spain
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Seville, Spain
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Malmo, Sweden
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Mölndal, Sweden
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Stockholm, Sweden
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Uppsala, Sweden
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London, Greater London, United Kingdom
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Isleworth, Middlesex, United Kingdom
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Glasgow, Renfrewshire, United Kingdom
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Bath, United Kingdom
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Swindon, United Kingdom
Facility #2

Los Angeles, California, 90024, United States
Facility #2

New Haven, Connecticut, 06510, United States
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Boca Raton, Florida, 33486, United States
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Leesburg, Florida, 34749, United States
Facility #2

Miami, Florida, 33137, United States
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Tampa, Florida, 33613, United States
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Atlanta, Georgia, 30308, United States
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Boston, Massachusetts, 02118, United States
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New York, New York, 10021, United States
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Rochester, New York, 14623, United States
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Oklahoma City, Oklahoma, 73116, United States
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Portland, Oregon, 97210, United States
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Dallas, Texas, United States
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San Antonio, Texas, 78229, United States
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London, Ontario, Canada
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Berlin, Germany
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Roma, Italy
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Seoul, South Korea
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Madrid, Spain
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London, United Kingdom
Facility #3

Los Angeles, California, 90024, United States
Facility #3

Miami, Florida, 33145, United States
Facility #3

Tampa, Florida, 33609, United States
Facility #3

San Antonio, Texas, 78229, United States
Facility #3

Berlin, Germany
Facility #3

Roma, Italy
Facility #3

Seoul, South Korea
Facility #4

Seoul, South Korea

Conditions

Explore the condition pages connected to this study.

ALZHEIMER'S DISEASE