Could old drugs beat long COVID? major trial launches
NCT ID NCT06928272
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 29 times
Summary
This study tests two existing medications (upadacitinib and pirfenidone) to see if they can reduce Long COVID symptoms like fatigue, breathing trouble, brain fog, and pain. About 348 adults from six countries who have had COVID-19 and symptoms for at least three months will take a drug or a placebo for three months. The goal is to find a safe, effective treatment to improve daily life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre de Recherche du CHUS (CRCHUS)
RECRUITINGSherbrooke, Quebec, J1H 5N4, Canada
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INMI Lazzaro Spallanzani IRCCS
NOT_YET_RECRUITINGRoma, Roma, 00149, Italy
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Ini-Fiocruz
RECRUITINGRio de Janeiro, Rio de Janerio, 21040-900, Brazil
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Institut de Recherches Cliniques de Montréal (IRCM)
RECRUITINGMontreal, Quebec, H2W 1R7, Canada
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Joint Clinical Research Centre (JCRC)
NOT_YET_RECRUITINGKampala, Kampala, 10005, Uganda
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Laura Rodriguez Research Institute
RECRUITINGSan Diego, California, 92101, United States
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Sapienza Università di Roma
NOT_YET_RECRUITINGRoma, Roma, 00185, Italy
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University Teaching Hospital
NOT_YET_RECRUITINGLusaka, Lusaka Province, 10100, Zambia
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Università degli Studi di Modena e Reggio Emilia
NOT_YET_RECRUITINGModena, 41124, Italy
Conditions
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