New hope for esophageal cancer: triple therapy shows promise
NCT ID NCT06010303
First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 26 times
Summary
This study tests whether adding the experimental drug LBL-007 to standard immunotherapy (tislelizumab) and chemotherapy helps shrink tumors or delay cancer growth in people with advanced esophageal cancer that cannot be removed by surgery. About 118 adults with this type of cancer will receive either the triple combination or the standard two-drug regimen. The main goal is to see how many patients have their tumors shrink significantly.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Anhui Provincial Hospital
Hefei, Anhui, 230000, China
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Anyang Cancer Hospital
Anyang, Henan, 455001, China
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Changhua Christian Hospital
Changhua, 50006, Taiwan
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China Medical University Hospital
Taichung, 40447, Taiwan
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Chonnam National University Hwasun Hospital
HwasunGun, Jeollanam-do, 58128, South Korea
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Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Fujian Medical University Union Hospital
Fuzhou, Fujian, 350001, China
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General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 750004, China
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Harbin Medical University Cancer Hospital
Harbin, Heilongjiang, 150000, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450000, China
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Hrh Princess Maha Chakri Sirindhorn Medical Center (Srinakharinwirot University)
Ongkharak, 26120, Thailand
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Hunan Cancer Hospital
Changsha, Hunan, 410013, China
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Kaohsiung Medical University Chung Ho Memorial Hospital
Kaohsiung City, 807, Taiwan
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Lanzhou University Second Hospital
Lanzhou, Gansu, 730030, China
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Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School
Nanjing, Jiangsu, 210008, China
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Nantong Tumor Hospital Branch North
Nantong, Jiangsu, 226000, China
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Nanyang Central Hospital
Nanyang, Henan, 473000, China
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National Cancer Center
Goyang-si, Gyeonggi-do, 10408, South Korea
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National Taiwan University Hospital
Taipei, 10048, Taiwan
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China
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Phramongkutklao Hospital
Ratchathewi, 10400, Thailand
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Ramathibodi Hospital Mahidol University
Bangkok, 10400, Thailand
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Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 03080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, Seoul Teugbyeolsi, 03722, South Korea
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Shandong Cancer Hospital
Jinan, Shandong, 250117, China
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Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital
Chengdu, Sichuan, 610071, China
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Sichuan Cancer Hospital and Institute
Chengdu, Sichuan, 610041, China
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Siriraj Hospital
Bangkok, 10700, Thailand
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, 221000, China
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The Catholic University of Korea, Seoul St Marys Hospital
Seoul, Seoul Teugbyeolsi, 06591, South Korea
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The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, 230000, China
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The First Affiliated Hospital of Xinxiang Medical University
Xinxiang, Henan, 453100, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, 450052, China
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The First Peoples Hospital of Changzhou
Changzhou, Jiangsu, 213000, China
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The Second Affiliated Hospital of Shandong First Medical University
Taian, Shandong, 271099, China
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The Tumor Hospital Affiliated to Guangxi Medical University
Nanning, Guangxi, 530021, China
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Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, 300060, China
Conditions
Explore the condition pages connected to this study.