New pill tested for rare Brain-Related weight disorder

NCT ID NCT06046443

Completed Disease control Sponsor: Rhythm Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether a daily pill called LB54640 could help control weight in people with hypothalamic obesity, a rare condition where brain damage causes severe weight gain. For 14 weeks, 28 patients aged 12 and older took either the drug or a placebo pill, with some continuing for up to a year. Researchers measured changes in weight, body mass index (BMI), hunger levels, and safety to see if the treatment was effective and well-tolerated.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Birmingham Women's and Children's NHS Foundation Trust

Birmingham, B15 2TG, United Kingdom
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Columbia University

New York, New York, 10027, United States
Great Ormond Street Hospital for Children

London, WC1N 3JH, United Kingdom
Lynn Health Science Institute

Oklahoma City, Oklahoma, 73112, United States
St. Jude Children's Research Hospital

Memphis, Tennessee, 38105, United States
The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27514, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
University of Cambridge

Cambridge, CB2 1TN, United Kingdom
University of Iowa Children's Hospital

Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.

HYPOTHALAMIC OBESITY