Lung cancer combo shows promise after targeted therapy fails

NCT ID NCT05786430

First seen Feb 01, 2026 · Last updated May 15, 2026 · Updated 10 times

Summary

This study tests whether adding chemotherapy to the targeted drug lazertinib can help people with a specific type of advanced lung cancer (EGFR-mutant non-small cell lung cancer) whose cancer stopped responding to lazertinib alone. About 87 adults will receive the combination and be followed to see how long the cancer stays under control. The goal is to find a new treatment option when the first targeted therapy no longer works.

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Contacts and locations

Locations

  • Yonsei University Health System, Severance Hospital

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.